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Chemokine (C-X-C-motif) ligand 6 (CXCL6) is a small cytokine in the CXC chemokine family. It is a potent neutrophil chemoattractant and activator, and it shares broad similarities with other CXC chemokines such as IL-8 and ENA-78. CXCL6 promoted the release of MMP-9 from granulocytes, indicating its potential role as an inflammatory mediator. It functionally uses the IL-8/CXCL8 receptor to chemotaxis neutrophils, but this is structurally related to the epithelal-derived neutrophil attractor 78 (ENA-78)/CXCL5. The human CXCL6 gene has been cloned and physically mapped to the CXC chemokine locus on chromosome 4. Mature human CXCL6 is a 75-amino acid (AA) protein with a predicted molecular weight of approximately 8 kDa. The homology of human CXCL6 to mouse and bovine CXCL6 was 60% and 67%, respectively.
Recombinant Human C-X-C Motif Chemokine 6 expressed the target gene encoding Gly38-Asn114 with a 6His tag at the C-terminus.
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Trehalose, 1mM EDTA, pH 7.4.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water to a concentration not less than 100 μg/mL. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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Products are for research use only. Not for human use. We do not sell to patients.
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