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Recombinant Human Carboxypeptidase M (HEK293,C-6His)

Cat. No. M15014

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human Carboxypeptidase M (HEK293,C-6His) Structure
Synonym:

Carboxypeptidase M;CPM

Size Price Availability
10ug USD 240  USD240 4-7 Days
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Quality Control & Documentation
  • Purity: >95% , Endotoxin < 1 EU/ug
  • COA
  • MSDS
Biological Activity

Carboxypeptidase M (CPM) specifically removes c-terminal bases (arginine or lysine) from polypeptides and proteins. Carboxypeptidase plays a role in physiological processes such as coagulation/fibrinolysis, inflammation, food digestion, hormone promotion and neuropeptide processing. CPM is thought to play an important role in controlling the activity of peptide hormones and growth factors on the cell surface, as well as in membrane localization and degradation of extracellular proteins. It is widely distributed in various tissues and cells. CPM is involved in peptide metabolism on cell surface and extracellular fluid. CPM is not only a protease, but also a binding partner for cell surface protein-protein interactions.

Chemical Information
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xianming Zhang, et al. J Biol Chem. Carboxypeptidase M is a positive allosteric modulator of the kinin B1 receptor

[2] Leah Marquez-Curtis, et al. Stem Cells. Carboxypeptidase M expressed by human bone marrow cells cleaves the C-terminal lysine of stromal cell-derived factor-1alpha: another player in hematopoietic stem/progenitor cell mobilization?

[3] Cora Keil, et al. J Mol Biol. Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain

[4] R B Craveiro, et al. Braz J Med Biol Res. High expression of human carboxypeptidase M in Pichia pastoris: purification and partial characterization

[5] Jingqiu Li, et al. Gene. Structure of the human carboxypeptidase M gene. Identification of a proximal GC-rich promoter and a unique distal promoter that consists of repetitive elements

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Keywords: Recombinant Human Carboxypeptidase M (HEK293,C-6His), Carboxypeptidase M;CPM supplier, Cytokines and Growth Factors, inhibitors, activators

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