All AbMole products are for research use only, cannot be used for human consumption.
Expression host: CHO cells
Purity: > 95%. Sds-page gel and HIGH performance liquid chromatography were used
Endotoxin: < 0.01 EU/μg
Storage and stability: stored at 2~8℃, valid for 24 months. In case of separate packaging, store in -20℃ storage period of 6 months, -80℃ storage period of 12 months, avoid repeated freeze-thaw.
Bioactivity: CD16 is FcγR ⅲ, a glycoprotein with a molecular weight of 50-70kD, a member of Ig superfamily, known to be involved in antigen-dependent cytotoxicity (ADCC). The most significant feature of CD16 is that the cleavage triggered by membrane receptors is performed by NK cells. CD16 acts as a low affinity receptor for the Fc portion of some IgG, binding to the Fcε -associated receptor I (εRI of Fc) γ chain of CD3ζ and co-participates in signal transduction. NK cell CD16 directly leads to an increase in intracellular Ca+ levels and a cascade of biochemical reactions similar to T cell receptor activation.
| Storage | 2-8℃ |
[5] Y W Huang, et al. Stem Cells. Immunotherapy of multiple myeloma
| Related Cytokines and Growth Factors Products |
|---|
| Recombinant Human GDF-15 Protein (HEK293 N-hFc)
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily. GDF-15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression. |
| Recombinant Human FGFR1 Protein (HEK293, C-His)
FGFR1, also known as CD331, is a full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. |
| Recombinant Human FGFR2 Protein (HEK293, C-His)
FGFR2, also known as CD332, acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. FGFR2 plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. It also promotes cell proliferation in keratinocytes and imature osteoblasts, but promotes apoptosis in differentiated osteoblasts. |
| Recombinant Mouse BMP-4 Protein (E. coli, C-His)
Bone Morphogenetic Protein-4 (BMP-4) is a critical signaling molecule required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. BMP-4 is secreted from the dorsal portion of the notochord, and it acts in concert with sonic hedgehog to establish a dorsal-ventral axis for the differentiation of later structures. |
| Recombinant Human Coagulation Factor X (HEK293, C-Fc)
Coagulation factor X, belongs to the peptidase S1 family. Coagulation factor X is initially synthesized in the liver. Coagulation factor X is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
