Expression system: Mammalian
Apparent molecular weight: 50-60 kDa, reduction conditions
Endotoxin: less than 0.1 ng/µg (1 EU/µg) by LAL test
Purity: > 95% as determined by reduced SDS-PAGE
Storage and stability: Storage temperature ≤-70℃, stable storage for 6 months after receiving goods. After opening, store in aseptic condition for 3 months, storage temperature ≤-70℃. Please minimize freeze-thaw cycles.
Bioactivity: Beta1,4-Galactosyltransferase-I (B4GALT1), one of seven beta1,4-galactosyltransferases, is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. By sequence similarity, the beta 4GalTs form four groups: beta 4GalT1 and beta 4GalT2, beta 4GalT3 and beta 4GalT4, beta 4GalT5 and beta 4GalT6, and beta 4GalT7. beta 4GalT1 is unique among the seven enzymes because it can be expressed either as membrane associated form or secreted form. The secreted form is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha -lactalbumin to catalyze the synthesis of lactose. The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions, as those occurring during development and egg fertilization, by binding to specific oligosaccharide ligands on opposing cells or in the extracellular matrix. Defects in beta 4GalT1 are the cause of congenital disorder of glycosylation type 2D (CDG2D) .
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
|Purity||>95% , Endotoxin < 1 EU/µg|
|Related Cytokines Products|
|Recombinant Human S100A11（E.coli ）
The recombinant human protein S100-A11 was produced by the expression system of Escoli and the target gene Met1-Thr105 was expressed. Protein number: P31949.
|Recombinant Mouse S100A11 (E.coli , N-6His)
The recombinant mouse protein S100-A11 was produced by the Escoli expression system, and the target gene Met1-Ile98 was expressed with 6His marker at the n terminal. Protein number: P50543.
|Recombinant Human Transferrin (Mammalian, C-6His)
Recombinant human transferrin is produced by mammalian expression system, and the target gene is encoded as Val20-Pro698, which is expressed by 6His marker at the C-terminal. Protein number: AAA61140.1.
|Recombinant Human PD-1 (HEK293, His）
Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators.蛋白序列：DNA 序列编码人 PD-1（ NCBI Reference Sequence: NP_005009.2）表达带有 His 标签在 C 末端。
|Recombinant Rat TNF-α (P. pastoris)
Recombinant rat tumor necrosis factor produced in Pichia pastoris α （rrTNF- α） It is a glycosylated polypeptide chain containing 157 amino acids. rrTNF- α It is a completely biologically active molecule. Accession # P20826。
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.