Cat.No. | Name | Information |
---|---|---|
M4973 | BAPTA-AM | BAPTA-AM is a selective, membrane-permeable calcium chelator. BAPTA-AM inhibits hERG channels, hKv1.3 and hKv1.5 channels in HEK 293 cells with IC50s of 1.3 μM, 1.45 μM and 1.23 μM, respectively. |
M2181 | ML133 hydrochloride | ML133 hydrochloride is a selective inhibitor of the Kir2 family of inward rectifier (IRK, KCNJ) potassium channels. |
M3456 | Chlorpromazine hydrochloride | Chlorpromazine hydrochloride is an antagonist of D2, 5HT2A, potassium and sodium channels. The Ki of Chlorpromazine Hydrochloride to D2 and 5HT2A were 363 nM and 8.3 nM, respectively. Chlorpromazine also excites the 20S proteasome. *The compound is unstable in solutions, freshly prepared is recommended |
M7029 | Nigericin sodium salt | Nigericin (NSC 292567) sodium salt is a selective K+ ionophore, Nigericin sodium salt is also an NLRP3 activator which can activate NLRP3 inflammasome to induce pro-inflammatory and immunostimulatory processes. |
M9423 | CLP290 | CLP290 is a novel, orally available KCC2 modulator, highly selective for KCC2 over related Cl- transporters. |
M9394 | BMS-191011 | BMS-191011 is a potent BKCa channel opener (large-conductance Ca2+-activated potassium channel, KCa1.1). |
M8906 | Sematilide hydrochloride | Sematilide (CK-1752) hydrochloride is a novel class III antiarrhythmic agent. |
M8698 | Kurarinone | Kurarinone, a flavanone from Sophora flavescens roots, is a potent activator of the large-conductance calcium-activated potassium channel (BKCa channel). |
M8223 | VU591 | VU591 is a Potassium Inwardly-Rectifying Channel (KCNJ1 or ROMK) specific inhibitor (IC50 = 240 nM) that is closely related to VU590. |
M7926 | Minoxidil | Minoxidil activates ATP-activated K+ channels; vasodilator; slow or stop hair loss and promote hair regrowth. |
M7826 | 5-Hydroxydecanoic acid sodium salt | 5-hydroxydecanoate (5-HD) blocks post-ischemic actions of the K+ channel activator cromakalim. |
M7299 | SKA 31 | SKA 31 is a activator of K Ca3.1 and K Ca2 channels. |
M7177 | Quinine hydrochloride | Quinine hydrochloride is the hydrochloride form of Quinine, an alkaloid extracted from the bark of the cinchona tree, with antimalarial and antitumor activities, and an IC50 value of 60 ng/mL against P. falciparum strains passou and 107.8 ng/mL against P. falciparum strain 3CD7, respectively, and an inhibitor of potassium channels. Quinine hydrochloride is also a potassium channel inhibitor that inhibits voltage pulse-induced MT mSlo3 (KCa5.1) channel +100 mV currents, with an IC50 value of 169 μM. In addition, Quinine hydrochloride binds to purine nucleoside phosphorylase (PfNP) and PfNP with low nanomolar affinity. nucleoside phosphorylase (PfPNP) with low nanomolar affinity. |
M7103 | Paxilline | Paxilline is a sERCA ATPase blocker. Also potent BK Ca channel blocker. |
M7052 | NS 5806 | NS 5806 is a k V4.3 channel activator. |
M7029 | Nigericin sodium salt | Nigericin (NSC 292567) sodium salt is a selective K+ ionophore, Nigericin sodium salt is also an NLRP3 activator which can activate NLRP3 inflammasome to induce pro-inflammatory and immunostimulatory processes. |
M6981 | ML 365 | ML 365 is a potent and selective K2P3.1 TASK-1 channel blocker. |
M6975 | ML297 | ML297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator. |
M6906 | Levcromakalim | Levcromakalim is a k ir6 (K ATP) channel opener; active enantiomer of cromakalim. |
M6735 | Flupirtine maleate | Flupirtine maleate is a selective potassium channel opener, NMDA receptor antagonist and GABAA receptor modulator. |
M6580 | Cesium chloride | Cesium chloride is a potassium channel blocker; neuroprotective. |
M6323 | 1-EBIO | 1-EBIO is a activator of epithelial K Ca channels. |
M6161 | GSK369796 Dihydrochloride | GSK369796 shows antimalerial activity with IC50 values of 11.2 nM for 3D7 strain, 12.6 nM for HB3 strain, 17.6 nM for K1 strain. |
M6052 | Vernakalant HCl | Vernakalant Hcl(RSD-1235) is an investigational mixed ion channel blocker that can terminate acute atrial fibrillation (AF) in humans at 2 to 5 mg/kg and may be more atrial-selective than available agents; in treatment of antiarrhythmic. |
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