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Retigabine is a novel anticonvulsant with activity in a broad range of seizure models. The mechanism of action involves opening of neuronal K(V)7.2-7.5 (formerly KCNQ2-5) voltage-activated K(+) channels.
Advanced Science. 2024 Jun 28.
Obstructive Sleep Apnea Syndrome Exacerbates NASH Progression via Selective Autophagy-Mediated Eepd1 Degradation
Retigabine 2HCl purchased from AbMole
| Molecular Weight | 376.25 |
| Formula | C16H20Cl2FN3O2 |
| CAS Number | 150812-13-8 |
| Solubility (25°C) | DMSO 50 mg/mL Water 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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