All AbMole products are for research use only, cannot be used for human consumption.
Chlorpromazine hydrochloride is an antagonist of D2, 5HT2A, potassium and sodium channels. The Ki of Chlorpromazine Hydrochloride to D2 and 5HT2A were 363 nM and 8.3 nM, respectively. Chlorpromazine hydrochloride also blocks hNav1.7 channels (IC50=25.9 μM; concentration-dependent) and HERG potassium channels (IC50=21.6 μM). Chlorpromazine also excites the 20S proteasome. Chlorpromazine hydrochloride also can inhibit clathrin-mediated endocytosis.
*The compound is unstable in solutions, freshly prepared is recommended.
Med Microbiol Immunol. 2024 Oct 23;213(1):23.
The pathogenic responses elicited during exposure of human intestinal cell line with Giardia duodenalis excretory-secretory products and the potential attributed endocytosis mechanism
Chlorpromazine hydrochloride purchased from AbMole
Mater Adv. 2024 Jul 18.
MiRNA-20a-loaded graphene oxide–polyethylenimine enters bone marrow mesenchymal stem cells via clathrin-dependent endocytosis for efficient osteogenic differentiation
Chlorpromazine hydrochloride purchased from AbMole
Small. 2023 Mar 12;e2208063.
2D MoS2 Nanosheets Induce Ferroptosis by Promoting NCOA4-Dependent Ferritinophagy and Inhibiting Ferroportin
Chlorpromazine hydrochloride purchased from AbMole
J Med Virol. 2023 Jan;95(1).
Enterovirus-71 utilizes small extracellular vesicles to cross the blood-brain barrier for infecting the central nervous system via transcytosis
Chlorpromazine hydrochloride purchased from AbMole
| Molecular Weight | 355.33 |
| Formula | C17H19ClN2S.HCl |
| CAS Number | 69-09-0 |
| Form | Solid |
| Solubility (25°C) | Water 90 mg/mL DMSO ≥ 60 mg/mL |
| Storage | -20°C, protect from light, dry, sealed |
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Products are for research use only. Not for human use. We do not sell to patients.
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