All AbMole products are for research use only, cannot be used for human consumption.
VU591 is a Potassium Inwardly-Rectifying Channel (KCNJ1 or ROMK) specific inhibitor (IC50 = 240 nM) that is closely related to VU590. Unlike VU590, VU591 does not inhibit Kir7.1. The compound has a modest effect on Kir6.2/SUR1, causing 17% inhibition at 10 uM.
| Molecular Weight | 368.3 |
| Formula | C16H12N6O5 |
| CAS Number | 1222810-74-3 |
| Form | Solid |
| Solubility (25°C) | DMSO: ≥12 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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