Potassium Channel Potassium channel

Cat.No.	Name	Information
M4973	BAPTA-AM	BAPTA-AM is a selective, membrane-permeable calcium chelator. BAPTA-AM inhibits hERG channels, hKv1.3 and hKv1.5 channels in HEK 293 cells with IC50s of 1.3 μM, 1.45 μM and 1.23 μM, respectively.
M2181	ML133 hydrochloride	ML133 hydrochloride is a selective inhibitor of the Kir2 family of inward rectifier (IRK, KCNJ) potassium channels.
M3456	Chlorpromazine hydrochloride	Chlorpromazine hydrochloride is an antagonist of D2, 5HT2A, potassium and sodium channels. The Ki of Chlorpromazine Hydrochloride to D2 and 5HT2A were 363 nM and 8.3 nM, respectively. Chlorpromazine also excites the 20S proteasome. *The compound is unstable in solutions, freshly prepared is recommended
M7029	Nigericin sodium salt	Nigericin (NSC 292567) sodium salt is a selective K⁺ ionophore, Nigericin sodium salt is also an NLRP3 activator which can activate NLRP3 inflammasome to induce pro-inflammatory and immunostimulatory processes.
M20428	Retigabine 2HCl	Retigabine is a novel anticonvulsant with activity in a broad range of seizure models. The mechanism of action involves opening of neuronal K(V)7.2-7.5 (formerly KCNQ2-5) voltage-activated K(+) channels.
M9780	Nigericin	Nigericin is an antibiotic derived from Streptomyces hygroscopicus, it acts as an H+, K+, Pb2+ ionophore.
M2724	Gliquidone	Gliquidone is an ATP-sensitive K⁺ channel antagonist with IC50 of 27.2 nM.
M2649	Doxapram hydrochloride hydrate	Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
M2043	TAK-438	TAK-438 is a novel and potent potassium-competitive acid blocker (P-CAB) with IC50 of 19 nM.
M1553	4-Hydroxytolbutamide	4-Hydroxytolbutamide
M56564	QO 58	QO 58 is a potent modulator of K(v)7 channels.
M56563	NS3623	NS3623 is an activator of human ether-a-go-go-related gene (hERG1/KV11.1) potassium channels.
M56562	ML67-33	ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels.
M56561	A-935142	A-935142 is a human ether-a-go-go-related gene (hERG, Kv 11.1) channel activator.
M56560	Naminidil	Naminidil is a cyanoguanidine KATP opener.
M56559	6-Bnz-cAMP	6-Bnz-cAMP (N6-Benzoyl-cAMP), a derivative of cyclic adenosine monophosphate (cAMP), is a potent inhibitor of the bTREK-1 potassium channel.
M56558	BMS-986308	BMS-986308 is a selective and orally active renal outer medullary potassium (ROMK) channel inhibitor.
M56557	RU-TRAAK-2	RU-TRAAK-2 is a completely reversible TRAAK (TWIK-related arachidonic acid-stimulated K+ channel) inhibitor.
M56556	Atpenin A5	Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM), and is an effective mKATP channel agonist and cardioprotective agent.
M56555	Cibenzoline	Cibenzoline is a potent inhibitor of KATP channel with directly affecting the pore-forming Kir6.2 subunit rather than the SUR1 subunit.
M56554	GoSlo-SR-5-69	GoSlo-SR-5-69 is a potent activator of large conductance Ca2+-activated K+ (BK) channels, with an EC50 of 251 nM.
M55233	CVN293	CVN293 is a selective and brain permeable potassium (K+) ion channel KCNK13 inhibtor with IC50s of 41 nM and 28 nM for hKCNK13 and mKCNK13, respectively.
M54578	NPBA	NPBA is a potassium K2P channel TASK-3 (KCNK9) agonist and a tandem pore domain weak inward rectifier K+ channel (TWIK2) channel blocker. In addition, NPBA inhibits the activation of NLRP3 inflammasome in macrophages.
M54154	BeKm-1	BeKm-1 is a HERG (human ether-a-go-go-related gene) blocking compound.
M53905	Phe-Met-Arg-Phe amide trifluoroacetate	Phe-Met-Arg-Phe amide trifluoroacetate is an activator of K+ current, with ED50 of 23 nM in the peptidergic caudodorsal neurons.
M53840	Iberiotoxin	Iberiotoxin is a toxin isolated from Buthus tamulus scorpion venom.

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Potassium Channel Potassium channel

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