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Doxapram hydrochloride hydrate

Cat. No. M2649

All AbMole products are for research use only, cannot be used for human consumption.

Doxapram hydrochloride hydrate Structure
Synonym:

Doxapram HCl

Size Price Availability Quantity
25mg USD 45  USD45 In stock
50mg USD 65  USD65 In stock
100mg USD 100  USD100 In stock
200mg USD 160  USD160 In stock
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Quality Control & Documentation
Biological Activity

Doxapram hydrochloride hydrate inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.

Chemical Information
Molecular Weight 432.98
Formula C24H30N2O2.HCl.H2O
CAS Number 7081-53-0
Form Solid
Solubility (25°C) DMSO 70 mg/mL
Water 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Robert B Flint, et al. The bioavailability and maturing clearance of doxapram in preterm infants

[2] Cornelia G de Waal, et al. Doxapram Treatment and Diaphragmatic Activity in Preterm Infants

[3] Roseanne J S Vliegenthart, et al. Doxapram Treatment for Apnea of Prematurity: A Systematic Review

[4] M L Cohn. Letter: Doxapram hydrochloride

[5] S C Wang, et al. Doxapram

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Keywords: Doxapram hydrochloride hydrate, Doxapram HCl supplier, Potassium Channel, inhibitors, activators

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