All AbMole products are for research use only, cannot be used for human consumption.
Nigericin sodium salt is a potassium ionophore, exchanges K+ for H+ across biological membranes, in a similar manner to Valinomycin. Stimulates mitochondral ATPase activity and disrupts membrane potential. Also acts as an ionophore for Pb2+ with no activity with other divalent cations. Antibiotic derived from Streptomyces hygroscopius. Nigericin sodium salt is also an NLRP3 activator which can activate NLRP3 inflammasome to induce pro-inflammatory and immunostimulatory processes.
Sci Rep. 2024 Sep 13;14(1):21410.
ROS exhaustion reverses the effects of hyperbaric oxygen on hemorrhagic transformation through reactivating microglia in post-stroke hyperglycemic mice
Nigericin sodium salt purchased from AbMole
Sci Rep. 2024 Sep 13;14(1):21410.
ROS exhaustion reverses the effects of hyperbaric oxygen on hemorrhagic transformation through reactivating microglia in post-stroke hyperglycemic mice
Nigericin sodium salt purchased from AbMole
Parasit Vectors. 2024 Nov 29;17(1):495.
The microneme protein1 (MIC1) of Chinese 1 Toxoplasma regulates pyroptosis through the TLR4/NLRP3 pathway in macrophages
Nigericin sodium salt purchased from AbMole
Brain Research. 2024 Jan.
Black phosphorus nanosheets inhibit glioblastoma cell migration and invasion through modulation of WNT/β-catenin and NOTCH signaling pathways
Nigericin sodium salt purchased from AbMole
Brain Res. 2023 Dec;14:1825:148710.
Electroacupuncture stimulation ameliorates cognitive impairment induced by long-term high-fat diet by regulating microglial BDNF
Nigericin sodium salt purchased from AbMole
| Molecular Weight | 746.94 |
| Formula | C40H67NaO11 |
| CAS Number | 28643-80-3 |
| Solubility (25°C) | Ethanol ≥ 30 mg/mL |
| Storage | 2-8°C, dry, protect from light, sealed |
| Related Potassium Channel Products |
|---|
| VU0810464
VU0810464 is a potent and selective non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. VU0810464 displays nanomolar potency for neuronal (EC50=165 nM) and GIRK1/4 (EC50=720 nM) channels with improved brain penetration. |
| QO 58
QO 58 is a potent modulator of K(v)7 channels. |
| NS3623
NS3623 is an activator of human ether-a-go-go-related gene (hERG1/KV11.1) potassium channels. |
| ML67-33
ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels. |
| A-935142
A-935142 is a human ether-a-go-go-related gene (hERG, Kv 11.1) channel activator. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
