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Dopamine Receptor Dopamine Receptor

Cat.No.  Name Information
M5686 Haloperidol Haloperidol is a potent dopamine D2 receptor antagonist.
M9049 MPTP HCl MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease.
M2472 Bromocriptine Mesylate Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.
M2988 Ropinirole Ropinirole is a dopamine agonist in non-ergoline compounds.
M2987 Ropinirole hydrochloride Ropinirole a selective dopamine D2 receptors inhibitor with IC50 of 29 nM.
M2945 Pimozide Pimozide is an antagonist of 6-hydroxyapatide against 6-hydroxyapatide, with Ki values of 1.4 nM, 2.5 nM and 588 nM for 6-hydroxyapatide, D3 and D1 receptors, respectively. Pimozide also has a high affinity for α1-adrenoceptor. Ki value is 39 nM. Pimozide is also an inhibitor of STAT3 and STAT5, and piperimidate triggers ADCD in glioblastoma cell lines (LN-229, MZ-54, GOS-3 and U343) by inducing dephosphorylation and inactivation of mTORC1.
M2936 Phenothiazine Phenothiazine is a dopamine-2 (D2) receptor antagonist therefore decreases the effect of dopamine in the brain.
M2925 Pergolide mesylate Pergolide mesylate is an antiparkinsonian agent which functions as a dopaminergic agonist.
M2886 Nomifensine Maleate Nomifensine is a dopamine reuptake inhibitor that increases the amount of synaptic dopamine available to receptors by blocking dopamine's re-uptake transporter.
M2655 Droperidol Droperidol is a potent antagonist of dopamine subtype 2 receptors in the limbic system.
M2494 Cariprazine hydrochloride Cariprazine hydrochloride is a dopamine D3-receptor-preferring partial agonist that exhibits high selectivity and affinity to dopamine D3 and D2(L/S) receptors with pKi 10.07 and 9.16/9.31, respectively.
M2415 Azaperone Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic compound with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.
M2372 Alizapride hydrochloride Alizapride hydrochloride is a dopamine receptor antagonist used for the theropy of nausea and vomiting.
M1915 Naxagolide Naxagolide (Dopazinol) is a very potent and selective D2 agonist.
M1910 Nepicastat hydrochloride Nepicastat hydrochloride is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively.
M44845 D-Tetrahydropalmatine D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis.
M42176 Ensaculin free base Ensaculin free base (KA-672) is a NMDA antagonist and have high affinities to serotonergic 5-HT1A and 5-HT7 receptors, adrenergic α1, and dopaminergic D2 and D3 receptors.
M41815 NPEC-caged-dopamine NPEC-caged-dopamine is a caged version of dopamine.
M41814 D4R agonist-1 D4R agonist-1 is a D4R partial agonist (Ki: 2.2 nM).
M41813 SKF 83822 SKF 83822 is an atypical agonist of dopamine D1 receptor.
M41812 SKF-75670 hydrobromide SKF-75670 hydrochloride is a Dopamine D1 receptor partial agonist.
M41811 GBR-12879 dihydrochloride GBR-12879 dihydrochloride is a potent inhibitor of dopamine uptake.
M41810 D3R/MOR antagonist 2 D3R/MOR antagonist 2 is a D3R/MOR antagonist (Ki: 361 nM and 85.2 nM respectively).

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