| Cat.No. | Name | Information |
|---|---|---|
| M5686 | Haloperidol | Haloperidol is a potent dopamine D2 receptor antagonist. |
| M9049 | MPTP HCl | MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease. |
| M2472 | Bromocriptine Mesylate | Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes. |
| M2988 | Ropinirole | Ropinirole is a dopamine agonist in non-ergoline compounds. |
| M2987 | Ropinirole hydrochloride | Ropinirole a selective dopamine D2 receptors inhibitor with IC50 of 29 nM. |
| M2945 | Pimozide | Pimozide is an antagonist of 6-hydroxyapatide against 6-hydroxyapatide, with Ki values of 1.4 nM, 2.5 nM and 588 nM for 6-hydroxyapatide, D3 and D1 receptors, respectively. Pimozide also has a high affinity for α1-adrenoceptor. Ki value is 39 nM. Pimozide is also an inhibitor of STAT3 and STAT5, and piperimidate triggers ADCD in glioblastoma cell lines (LN-229, MZ-54, GOS-3 and U343) by inducing dephosphorylation and inactivation of mTORC1. |
| M2936 | Phenothiazine | Phenothiazine is a dopamine-2 (D2) receptor antagonist therefore decreases the effect of dopamine in the brain. |
| M2925 | Pergolide mesylate | Pergolide mesylate is an antiparkinsonian agent which functions as a dopaminergic agonist. |
| M2886 | Nomifensine Maleate | Nomifensine is a dopamine reuptake inhibitor that increases the amount of synaptic dopamine available to receptors by blocking dopamine's re-uptake transporter. |
| M2655 | Droperidol | Droperidol is a potent antagonist of dopamine subtype 2 receptors in the limbic system. |
| M2494 | Cariprazine hydrochloride | Cariprazine hydrochloride is a dopamine D3-receptor-preferring partial agonist that exhibits high selectivity and affinity to dopamine D3 and D2(L/S) receptors with pKi 10.07 and 9.16/9.31, respectively. |
| M2415 | Azaperone | Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic compound with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine. |
| M2372 | Alizapride hydrochloride | Alizapride hydrochloride is a dopamine receptor antagonist used for the theropy of nausea and vomiting. |
| M1915 | Naxagolide | Naxagolide (Dopazinol) is a very potent and selective D2 agonist. |
| M1910 | Nepicastat hydrochloride | Nepicastat hydrochloride is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively. |
| M44845 | D-Tetrahydropalmatine | D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis. |
| M42176 | Ensaculin free base | Ensaculin free base (KA-672) is a NMDA antagonist and have high affinities to serotonergic 5-HT1A and 5-HT7 receptors, adrenergic α1, and dopaminergic D2 and D3 receptors. |
| M41815 | NPEC-caged-dopamine | NPEC-caged-dopamine is a caged version of dopamine. |
| M41814 | D4R agonist-1 | D4R agonist-1 is a D4R partial agonist (Ki: 2.2 nM). |
| M41813 | SKF 83822 | SKF 83822 is an atypical agonist of dopamine D1 receptor. |
| M41812 | SKF-75670 hydrobromide | SKF-75670 hydrochloride is a Dopamine D1 receptor partial agonist. |
| M41811 | GBR-12879 dihydrochloride | GBR-12879 dihydrochloride is a potent inhibitor of dopamine uptake. |
| M41810 | D3R/MOR antagonist 2 | D3R/MOR antagonist 2 is a D3R/MOR antagonist (Ki: 361 nM and 85.2 nM respectively). |
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