Cat.No. | Name | Information |
---|---|---|
M5686 | Haloperidol | Haloperidol is a potent dopamine D2 receptor antagonist. |
M9049 | MPTP HCl | MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease. |
M2472 | Bromocriptine Mesylate | Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes. |
M20407 | Piribedil | Piribedil is a relatively selective dopamine (D2/D3) agonist with moderate antidepressant activity. It also has α2-adrenergic (α2A/α2C) antagonist properties. |
M20395 | Tetrabenazine (Xenazine) | Tetrabenazine(Nitoman, Xenazine) acts primarily as a reversible high-affinity inhibitor of mono-amine uptake into granular vesicles of presynaptic neurons by binding selectively to VMAT-2 Also blocks dopamine D2 receptors, but this affinity is 1,000-fold lower than its affinity for VMAT-2. |
M13954 | Zuclopenthixol | Zuclopenthixol is a thioxanthene derivative which acts as a mixed dopamine D1/D2 receptor antagonist. |
M13951 | Sultopride hydrochloride | Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. |
M13950 | Quinpirole Hydrochloride | Quinpirole Hydrochloride ((-)-LY 171555) is a high-affinity agonist of dopamine D2/D3 receptor. |
M13948 | Neuromedin N | Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. |
M8114 | PF-06412562 | PF-06412562 is a dopamine receptor D1 (DRD1) agonist ligand. |
M7693 | Chloro-APB hydrobromide | Chloro-APB hydrobromide is a selective dopamine D1 receptor agonist and induces dopamine D1 receptor-dependent adenylate cyclase activity in rat striatal membranes (EC50=491 nM). |
M6786 | Haloperidol hydrochloride | Haloperidol hydrochloride is a antagonist, partly D 2 selective. |
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