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Dopamine Receptor Dopamine Receptor

Cat.No.  Name Information
M5686 Haloperidol Haloperidol is a potent dopamine D2 receptor antagonist.
M9049 MPTP HCl MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease.
M2472 Bromocriptine Mesylate Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.
M20407 Piribedil Piribedil is a relatively selective dopamine (D2/D3) agonist with moderate antidepressant activity. It also has α2-adrenergic (α2A/α2C) antagonist properties.
M20395 Tetrabenazine (Xenazine) Tetrabenazine(Nitoman, Xenazine) acts primarily as a reversible high-affinity inhibitor of mono-amine uptake into granular vesicles of presynaptic neurons by binding selectively to VMAT-2 Also blocks dopamine D2 receptors, but this affinity is 1,000-fold lower than its affinity for VMAT-2.
M13954 Zuclopenthixol Zuclopenthixol is a thioxanthene derivative which acts as a mixed dopamine D1/D2 receptor antagonist.
M13951 Sultopride hydrochloride Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor.
M13950 Quinpirole Hydrochloride Quinpirole Hydrochloride ((-)-LY 171555) is a high-affinity agonist of dopamine D2/D3 receptor.
M13948 Neuromedin N Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes.
M8114 PF-06412562 PF-06412562 is a dopamine receptor D1 (DRD1) agonist ligand.
M7693 Chloro-APB hydrobromide Chloro-APB hydrobromide is a selective dopamine D1 receptor agonist and induces dopamine D1 receptor-dependent adenylate cyclase activity in rat striatal membranes (EC50=491 nM).
M6786 Haloperidol hydrochloride Haloperidol hydrochloride is a antagonist, partly D 2 selective.




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