Cat.No. | Name | Information |
---|---|---|
M5686 | Haloperidol | Haloperidol is a potent dopamine D2 receptor antagonist. |
M9049 | MPTP HCl | MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease. |
M2472 | Bromocriptine Mesylate | Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes. |
M20535 | Chlorpromazine | Chlorpromazine is an orally active, blood-brain barrier-transparent D2 dopamine receptors and 5-HT2A antagonist. Chlorpromazine also blocks hNav1.7 channels (IC50=25.9 μM; concentration-dependent) and HERG potassium channels (IC50=21.6 μM). |
M5590 | Dopamine HCl | Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis. |
M56178 | L 741742 hydrochloride | L 741742 hydrochloride is an orally active and selective antagonist of hD4 receptors. |
M56177 | GBR 12783 dihydrochloride | GBR 12783 dihydrochloride is a specific, potent and selective dopamine uptake inhibitor that inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively. |
M56176 | ent-Naxagolide hydrochloride | ent-Naxagolide (ent-MK-458) hydrochloride is a dopamine D2-receptor agonist. |
M54825 | SV 156 | SV 156 is a potent and selective D2 dopamine receptor antagonist, with a Ki of 2.5 nM for hD2. SV 156 has approximately 40-fold binding selectivity for D2 dopamine receptors compared to the D3 receptor subtype. |
M53201 | Cyclo(glycyl-L-leucyl) | Cyclo(glycyl-L-leucyl) (Cyclo(leu-gly)), a neuropeptide, down-regulates dopamine (DA) receptors and attenuates dopaminergic supersensitivity. |
M53200 | Onzigolide | Onzigolide (BIM-23A760), a chimeric dopamine-somatostatin compound, shows potent agonist activity at both DA type 2 (D2R) and SST type 2 (SSTR2) receptors. |
M49419 | CVL-871 | CVL-871 is a partial agonist at dopamine D1/5 receptors and may be used in dementia-related studies. |
M45359 | Melevodopa | Melevodopaa is an oral precursor compound to Levodopa that enters the body and can pass through the gut and blood-brain barrier into the brain. In the brain, Melevodopa is converted to dopamine, which increases dopamine levels in the brain and can be used in studies related to Parkinson's disease. |
M42176 | Ensaculin free base | Ensaculin free base (KA-672) is a NMDA antagonist and have high affinities to serotonergic 5-HT1A and 5-HT7 receptors, adrenergic α1, and dopaminergic D2 and D3 receptors. |
M41815 | NPEC-caged-dopamine | NPEC-caged-dopamine is a caged version of dopamine. |
M41814 | D4R agonist-1 | D4R agonist-1 is a D4R partial agonist (Ki: 2.2 nM). |
M41813 | SKF 83822 | SKF 83822 is an atypical agonist of dopamine D1 receptor. |
M41812 | SKF-75670 hydrobromide | SKF-75670 hydrochloride is a Dopamine D1 receptor partial agonist. |
M41811 | GBR-12879 dihydrochloride | GBR-12879 dihydrochloride is a potent inhibitor of dopamine uptake. |
M41810 | D3R/MOR antagonist 2 | D3R/MOR antagonist 2 is a D3R/MOR antagonist (Ki: 361 nM and 85.2 nM respectively). |
M41809 | D3R/MOR antagonist 1 | D3R/MOR antagonist 1 is a D3R/MOR antagonist (Ki: 46.5 nM and 691 nM respectively). |
M41808 | Bulbocapnine hydrochloride | Bulbocapnine hydrochloride, an aporphine alkaloid, is a dopamine receptor inhibitor. |
M41807 | PNU-177864 | PNU-177864 is a potent, selective and orally active dopamine D3 receptor antagonist. |
M41806 | FGH31 | FGH31 is a potent, selective, GRK2 dependency dopamine D4 agonist, with the Ki of 1.6 nM. |
M41805 | D1R antagonist 1 | D1R antagonist 1 is a D1R antagonist, involved in G-protein- and β-arrestin-based signaling. |
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