| Cat.No. | Name | Information |
|---|---|---|
| M5686 | Haloperidol | Haloperidol is a potent dopamine D2 receptor antagonist. |
| M9049 | MPTP HCl | MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease. |
| M2472 | Bromocriptine Mesylate | Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes. |
| M8498 | MLS1547 | MLS1547 is a highly efficacious D2 dopamine receptor (D2R) G protein-biased agonist that does not recruit β-arrestin, and is an antagonist of dopamine-stimulated β-arrestin recruitment to the D2 receptor. |
| M7825 | 6-Hydroxydopamine hydrobromide | 6-Hydroxydopamine hydrobromide is an antagonist of the neurotransmitter dopamine. It is a neurotoxin that disrupts catecholaminergic terminals. It is used in the study of Parkinson's disease (PD), attention deficit hyperactivity disorder (ADHD) and Leschner's syndrome.*The compound is unstable in solutions, freshly prepared is recommended |
| M7279 | SCH 23390 hydrochloride | SCH 23390 hydrochloride is a standard selective D 1-like antagonist; also 5-HT 2C and 5-HT 1C agonist and K ir3 channel blocker. |
| M6664 | Desipramine hydrochloride | Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT) and dopamine transporter (DAT) with Kis of 4, 61 and 78,720 nM, respectively. |
| M6372 | A 77636 hydrochloride | A 77636 hydrochloride is a potent, selective D 1-like agonist. Orally active. |
| M6370 | A 68930 hydrochloride | A 68930 hydrochloride is a potent, selective D 1-like agonist. |
| M6366 | A 412997 dihydrochloride | A 412997 dihydrochloride is a selective D 4 agonist. |
| M6279 | Laropiprant | Laropiprant is a potent, selective DP1 receptor antagonist with Ki value of 0.57 nM, and exhibits > 1,000 fold selectivity over DP2 receptor (Ki=0.75 μM). |
| M6196 | Fupentixol dihydrochloride | Flupentixol dihydrochloride, a thioxanthene drug, is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders. |
| M5984 | Sulpiride | Sulpiride is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. |
| M5914 | rac-Rotigotine (Hydrochloride) | rac-Rotigotine Hcl is a high potency and selectivity agonist for D-2 receptor with Ki of 0.69 nM. |
| M5903 | Promazine HCl | Promazine (hydrochloride) is a D2 dopamine receptor antagonist, belongs to the phenothiazine class of antipsychotics, used to treat schizophrenia. |
| M5900 | Prochlorperazine dimaleate salt | Prochlorperazine dimaleate is a dopamine (D2) receptor antagonist. |
| M5891 | Pramipexole dihydrochloride | Pramipexole 2Hcl is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively. |
| M5872 | Perphenazine | Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties. |
| M5854 | SB 277011 Hydrochloride | Ligands acting as DRD3 antagonists (SB 277011-A) has shown some promise for reducing the influence of drug-associated cues on motivational behaviour. |
| M5848 | Paliperidone | Paliperidone, the main active metabolite of Risperidone, is a dopamine D2 antagonist and 5-HT2A antagonist. Paliperidone is also active as an antagonist at α1 and α2 adrenergic receptors and H1-histaminergic receptors. |
| M5796 | Molindone HCl | Molindone is an antipsychotic compound used to study schizophrenia that reduces psychosis by blocking the action of dopamine in the brain. |
| M5739 | Levosulpiride | Levosulpiride is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent. |
| M5642 | Fenoldopam mesylate | Fenoldopam is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation. |
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