| Cat.No. | Name | Information |
|---|---|---|
| M5686 | Haloperidol | Haloperidol is a potent dopamine D2 receptor antagonist. |
| M9049 | MPTP HCl | MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease. |
| M2472 | Bromocriptine Mesylate | Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes. |
| M20535 | Chlorpromazine | Chlorpromazine is an orally active, blood-brain barrier-transparent D2 dopamine receptors and 5-HT2A antagonist. Chlorpromazine also blocks hNav1.7 channels (IC50=25.9 μM; concentration-dependent) and HERG potassium channels (IC50=21.6 μM). |
| M5590 | Dopamine HCl | Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis. |
| M25565 | Lauflumide | Lauflumide is the common alternative of modafinil. Modafinil is commonly prescribed for the research narcolepsy. |
| M21844 | Acetophenazine dimaleate | Acetophenazine dimaleate primarily blocks dopamine D2 receptors in the brain. Acetophenazine dimaleate can be used for the research of psychotic disorders. |
| M20979 | ONC206 | ONC206 is a selective antagonist of dopamine D2-like receptor (DRD2) and has broad-spectrum anti-tumor activity. |
| M20407 | Piribedil | Piribedil is a relatively selective dopamine (D2/D3) agonist with moderate antidepressant activity. It also has α2-adrenergic (α2A/α2C) antagonist properties. |
| M13953 | Tetrahydropalmatine hydrochloride | Tetrahydropalmatine (DL-Tetrahydropalmatine) hydrochloride possesses analgesic effects. Tetrahydropalmatine hydrochloride acts through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats. |
| M13949 | Nomifensine | Nomifensine is a norepinephrine-dopamine reuptake inhibitor, increases the amount of synaptic norepinephrine and dopamine available to receptors by blocking the dopamine and norepinephrine reuptake transporters. |
| M11167 | A-381393 | A-381393 IS AN EFFECTIVE, SELECTIVE, AND BLOOD-BRAIN BARRIER-PERMEABLE dopamine D4 receptor Antagonist, dopamine D for humans4.4，D4.2 AND D4.7 receptors Ki The values are 1.5, 1.9, and 1.6 nM, respectively, with selectivity being D1，D2，D3，D5 MORE THAN 2700 TIMES THE DOPAMINE RECEPTOR. A-381393 VS. 5-HT2A MODERATE SELECTIVITY, Ki The value is 370 nM. |
| M10724 | Pridopidine | Pridopidine is a dopamine (DA) stabilizer that acts as a low-affinity dopamine D2 receptor (D2R) antagonist. Pridopidine high affinity acts on sigma 1 receptor (S1R),Ki Values of 70 to 80 nM are approximately 100 times higher than their affinity for D2R. |
| M10494 | ML417 | ML417 is a highly selective and brain penetrant D3 dopamine receptor (D3R) agonist, with EC50 of 38 nM. |
| M9601 | Cariprazine | Cariprazine is a D2 and D3 receptor partial agonist, with high selectivity towards the D3 receptor. |
| M9482 | PD-168077 maleate | PD-168077 maleate is a potent D4 dopamine receptor agonist (Ki = 8.7 nM), with > 400-fold and > 300-fold selectivity over D2 / D3 subtypes, respectively. |
| M9099 | SCH23390 | SCH23390 is a potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively). |
| M9022 | SKF38393 HCl | SKF38393 HCl is a selective D1 dopamine receptor agonist with IC50 of 110 nM. |
| M8498 | MLS1547 | MLS1547 is a highly efficacious D2 dopamine receptor (D2R) G protein-biased agonist that does not recruit β-arrestin, and is an antagonist of dopamine-stimulated β-arrestin recruitment to the D2 receptor. |
| M7825 | 6-Hydroxydopamine hydrobromide | 6-Hydroxydopamine hydrobromide is an antagonist of the neurotransmitter dopamine. It is a neurotoxin that disrupts catecholaminergic terminals. It is used in the study of Parkinson's disease (PD), attention deficit hyperactivity disorder (ADHD) and Leschner's syndrome.*The compound is unstable in solutions, freshly prepared is recommended |
| M7279 | SCH 23390 hydrochloride | SCH 23390 hydrochloride is a standard selective D 1-like antagonist; also 5-HT 2C and 5-HT 1C agonist and K ir3 channel blocker. |
| M6664 | Desipramine hydrochloride | Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT) and dopamine transporter (DAT) with Kis of 4, 61 and 78,720 nM, respectively. |
| M6372 | A 77636 hydrochloride | A 77636 hydrochloride is a potent, selective D 1-like agonist. Orally active. |
| M6370 | A 68930 hydrochloride | A 68930 hydrochloride is a potent, selective D 1-like agonist. |
| M6366 | A 412997 dihydrochloride | A 412997 dihydrochloride is a selective D 4 agonist. |
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