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Dopamine Receptor Dopamine Receptor

Inhibitors

Cat.No.  Name Information
M5686 Haloperidol Haloperidol is a potent dopamine D2 receptor antagonist.
M9099 SCH23390 SCH23390 is a potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively).
M9049 MPTP HCl MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease.
M9022 SKF38393 HCl SKF38393 HCl is a selective D1 dopamine receptor agonist with IC50 of 110 nM.
M7832 6-Hydroxydopamine hydrochloride 6-Hydroxydopamine hydrochloride is an antagonist of the neurotransmitter dopamine. *The compound is unstable in solutions, freshly prepared is recommended
M7279 SCH 23390 hydrochloride SCH 23390 hydrochloride is a standard selective D 1-like antagonist; also 5-HT 2C and 5-HT 1C agonist and K ir3 channel blocker.
M6664 Desipramine hydrochloride Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT) and dopamine transporter (DAT) with Kis of 4, 61 and 78,720 nM, respectively.
M5984 Sulpiride Sulpiride is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.
M5914 rac-Rotigotine (Hydrochloride) rac-Rotigotine Hcl is a high potency and selectivity agonist for D-2 receptor with Ki of 0.69 nM.
M5903 Promazine HCl Promazine (hydrochloride) is a D2 dopamine receptor antagonist, belongs to the phenothiazine class of antipsychotics, used to treat schizophrenia.
M5900 Prochlorperazine dimaleate salt Prochlorperazine dimaleate is a dopamine (D2) receptor antagonist.
M5891 Pramipexole dihydrochloride Pramipexole 2Hcl is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.
M5872 Perphenazine Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
M5854 SB 277011 Hydrochloride Ligands acting as DRD3 antagonists (SB 277011-A) has shown some promise for reducing the influence of drug-associated cues on motivational behaviour.
M5848 Paliperidone Paliperidone, the main active metabolite of Risperidone, is a potent serotonin-2A and dopamine-2 receptor antagonist, used in the treatment of schizophrenia.
M5796 Molindone HCl Molindone is an antipsychotic compound used to study schizophrenia that reduces psychosis by blocking the action of dopamine in the brain.
M5739 Levosulpiride Levosulpiride is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent.
M5686 Haloperidol Haloperidol is a potent dopamine D2 receptor antagonist.
M5642 Fenoldopam mesylate Fenoldopam is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.
M5590 Dopamine HCl Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.
M5525 Clebopride malate Clebopride malate is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders.



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