| Cat.No. | Name | Information |
|---|---|---|
| M5686 | Haloperidol | Haloperidol is a potent dopamine D2 receptor antagonist. |
| M9049 | MPTP HCl | MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease. |
| M2472 | Bromocriptine Mesylate | Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes. |
| M20535 | Chlorpromazine | Chlorpromazine is an orally active, blood-brain barrier-transparent D2 dopamine receptors and 5-HT2A antagonist. Chlorpromazine also blocks hNav1.7 channels (IC50=25.9 μM; concentration-dependent) and HERG potassium channels (IC50=21.6 μM). |
| M6196 | Fupentixol dihydrochloride | Flupentixol dihydrochloride, a thioxanthene drug, is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders. |
| M5984 | Sulpiride | Sulpiride is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. |
| M5914 | rac-Rotigotine (Hydrochloride) | rac-Rotigotine Hcl is a high potency and selectivity agonist for D-2 receptor with Ki of 0.69 nM. |
| M5903 | Promazine HCl | Promazine (hydrochloride) is a D2 dopamine receptor antagonist, belongs to the phenothiazine class of antipsychotics, used to treat schizophrenia. |
| M5900 | Prochlorperazine dimaleate salt | Prochlorperazine dimaleate is a dopamine (D2) receptor antagonist. |
| M5891 | Pramipexole dihydrochloride | Pramipexole 2Hcl is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively. |
| M5872 | Perphenazine | Perphenazine is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties. |
| M5854 | SB 277011 Hydrochloride | Ligands acting as DRD3 antagonists (SB 277011-A) has shown some promise for reducing the influence of drug-associated cues on motivational behaviour. |
| M5848 | Paliperidone | Paliperidone, the main active metabolite of Risperidone, is a dopamine D2 antagonist and 5-HT2A antagonist. Paliperidone is also active as an antagonist at α1 and α2 adrenergic receptors and H1-histaminergic receptors. |
| M5796 | Molindone HCl | Molindone is an antipsychotic compound used to study schizophrenia that reduces psychosis by blocking the action of dopamine in the brain. |
| M5739 | Levosulpiride | Levosulpiride is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent. |
| M5642 | Fenoldopam mesylate | Fenoldopam is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation. |
| M5590 | Dopamine HCl | Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis. |
| M5525 | Clebopride malate | Clebopride malate is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. |
| M5467 | Brexpiprazole | Brexpiprazole is a novel D2 dopamine and serotonin 1A partial agonist, called serotonin-dopamine activity modulator (SDAM), and a potent antagonist of serotonin 2A receptors, noradrenergic alpha 1B and 2C receptors. |
| M5410 | Amisulpride | Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. |
| M5350 | Octopamine hydrochloride | Octopamine (OA), a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. |
| M5198 | Fluphenazine dihydrochloride | Fluphenazine dihydrochloride is a phenothiazine-class D1DR and D2DR inhibitor. |
| M4962 | fluoroclebopride | In vitro binding affinity on alpha-2 receptor is inhibition of binding of [3H]- rauwolscine to rat cortex. |
| M4458 | Tetrahydroberberine | Tetrahydroberberine is an isoquinoline alkaloid isolated from corydalis tuber; has micromolar affinity for dopamine D(2) (pK(i) = 6.08) and 5-HT(1A) (pK(i) = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors (5-HT(1B), 5-HT(1D), 5-HT(3), and 5-HT(4); pK(i) < 5.00). |
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