Dopamine Receptor Dopamine Receptor

Inhibitors

Cat.No.	Name	Information
M5686	Haloperidol	Haloperidol is a potent dopamine D2 receptor antagonist.
M5410	Amisulpride	Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.
M5350	(+,-)-Octopamine	Octopamine (OA), a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates.
M5198	Fluphenazine dihydrochloride	Fluphenazine dihydrochloride is a phenothiazine-class D1DR and D2DR inhibitor.
M4942	Metoclopramide hydrochloride hydrate	Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is used as an antiemetic.
M3818	Rotigotine Hydrochloride	Rotigotine Hydrochloride (N-0923 Hydrochloride) is a pure agonist of the dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor.Ki 值分别为 0.71 nM (dopamine D3 receptor)，4-15 nM (D2，D5，D4 receptors)，83 nM (dopamine D1 receptor)。
M3785	Flupenthixol dihydrochloride	Flupenthixol dihydrochloride is a dopamine receptor antagonist which acts as a Neuroleptic agent as well as an antipsychotic.
M3675	Rotigotine	Rotigotine (N-0437; N-0923) is a dopamine receptor agonist, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor.Ki 值分别为 0.71 nM (dopamine D3 receptor)，4-15 nM (D2，D5，D4 receptors)，83 nM (dopamine D1 receptor)。
M3674	Metoclopramide	Metoclopramide is a dopamine D2 antagonist that is used as an antiemetic.
M3586	Pramipexole dihydrochloride Monohydrate	Pramipexole dihydrochloride Monohydrate is a partial/full D2S, D2L, D3, D4, receptor agonist with a Ki of 3.9, 2.2, 0.5, 5.1 nM.
M3338	Domperidone	Domperidone is a dopamine blocker and an antidopaminergic reagent.
M3287	PD128907 hydrochloride	PD 128907 hydrochloride is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor.
M3250	Vanoxerine dihydrochloride	Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent and selective dopamine receptor inhibitor.
M3246	Amfebutamone hydrochloride	Amfebutamone hydrochloride is a selective norepinephrine-dopamine reuptake inhibitor with IC50 of 6.5 and 3.4μM for the reuptake of dopamine and norepinephrine, respectively
M3242	Sumanirole Maleate	Sumanirole maleate is a highly selective dopamine D2 receptor agonist with binding affinity of 9 nM and EC50 of about 46 nM, exhibits >200-fold selectivity over the other dopamine receptor subtypes.
M3165	Prochlorperazine dimaleate	Prochlorperazine dimaleate is a D2 dopamine receptor antagonist.
M3088	Triflupromazine hydrochloride	Triflupromazine hydrochloride is a member of a family of phenothiazine compounds that are dopamine D1/D2 receptor antagonists.
M3087	Trifluoperazine dihydrochloride	Trifluoperazine is a dopamine D2 receptor inhibitor with IC50 of 1.1 nM.
M2987	Ropinirole hydrochloride	Ropinirole a selective dopamine D2 receptors inhibitor with IC50 of 29 nM.
M2945	Pimozide	Pimozide is an antagonist of 6-hydroxyapatide against 6-hydroxyapatide, with Ki values of 1.4 nM, 2.5 nM and 588 nM for 6-hydroxyapatide, D3 and D1 receptors, respectively. Pimozide also has a high affinity for α1-adrenoceptor. Ki value is 39 nM. Pimozide is also an inhibitor of STAT3 and STAT5, and piperimidate triggers ADCD in glioblastoma cell lines (LN-229, MZ-54, GOS-3 and U343) by inducing dephosphorylation and inactivation of mTORC1.
M2936	Phenothiazine	Phenothiazine is a dopamine-2 (D2) receptor antagonist therefore decreases the effect of dopamine in the brain.

Signaling Pathways

Product Type

Dopamine Receptor Dopamine Receptor

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