Cat.No. | Name | Information |
---|---|---|
M5686 | Haloperidol | Haloperidol is a potent dopamine D2 receptor antagonist. |
M9049 | MPTP HCl | MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease. |
M2472 | Bromocriptine Mesylate | Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes. |
M5796 | Molindone HCl | Molindone is an antipsychotic compound used to study schizophrenia that reduces psychosis by blocking the action of dopamine in the brain. |
M5739 | Levosulpiride | Levosulpiride is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent. |
M5642 | Fenoldopam mesylate | Fenoldopam is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation. |
M5590 | Dopamine HCl | Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis. |
M5525 | Clebopride malate | Clebopride malate is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. |
M5467 | Brexpiprazole | Brexpiprazole is a novel D2 dopamine and serotonin 1A partial agonist, called serotonin-dopamine activity modulator (SDAM), and a potent antagonist of serotonin 2A receptors, noradrenergic alpha 1B and 2C receptors. |
M5410 | Amisulpride | Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. |
M5350 | Octopamine hydrochloride | Octopamine (OA), a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. |
M5198 | Fluphenazine dihydrochloride | Fluphenazine dihydrochloride is a phenothiazine-class D1DR and D2DR inhibitor. |
M4962 | fluoroclebopride | In vitro binding affinity on alpha-2 receptor is inhibition of binding of [3H]- rauwolscine to rat cortex. |
M4458 | Tetrahydroberberine | Tetrahydroberberine is an isoquinoline alkaloid isolated from corydalis tuber; has micromolar affinity for dopamine D(2) (pK(i) = 6.08) and 5-HT(1A) (pK(i) = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors (5-HT(1B), 5-HT(1D), 5-HT(3), and 5-HT(4); pK(i) < 5.00). |
M3927 | Tetrahydropalmatine | Tetrahydropalmatine (THP) is a natural compound isolated from Corydalis turtschaninovii. |
M3818 | Rotigotine Hydrochloride | Rotigotine Hydrochloride (N-0923 Hydrochloride) is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Ki of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor. |
M3785 | Flupenthixol dihydrochloride | Flupenthixol dihydrochloride is a dopamine receptor antagonist which acts as a Neuroleptic agent as well as an antipsychotic. |
M3675 | Rotigotine | Rotigotine is a potent dopamine receptor agonist with Ki values of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors and dopamine D1 receptor. Rotigotine a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor. |
M3674 | Metoclopramide | Metoclopramide is a potent antagonist of 5-HT3 and dopamine D2 receptor, with IC50s of 308 nM and 483 nM, respectively. |
M3592 | Chlorprothixene | Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively. |
M3586 | Pramipexole dihydrochloride Monohydrate | Pramipexole dihydrochloride Monohydrate is a partial/full D2S, D2L, D3, D4, receptor agonist with a Ki of 3.9, 2.2, 0.5, 5.1 nM. |
M3339 | Pramipexole | Pramipexole is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively. |
M3338 | Domperidone | Domperidone is a dopamine blocker and an antidopaminergic reagent. |
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