Free shipping on all orders over $ 500

Sulpiride

Cat. No. M5984
Sulpiride Structure
Synonym:

Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil

Size Price Availability Quantity
100mg USD 54  USD60 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
Biological Activity

Sulpiride is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 341.43
Formula C15H23N3O4S
CAS Number 15676-16-1
Purity 99.37%
Solubility 68 mg/mL in DMSO
Storage at -20°C
References

Detecting potential adverse reactions of sulpiride in schizophrenic patients by prescription sequence symmetry analysis.
Lai EC, et al. PLoS One. 2014 Feb 27;9(2):e89795. PMID: 24587038.

Related Dopamine Receptor Products
ML417

ML417 is a highly selective and brain penetrant D3 dopamine receptor (D3R) agonist, with EC50 of 38 nM.

Cariprazine

Cariprazine is a D2 and D3 receptor partial agonist, with high selectivity towards the D3 receptor.

PD-168077 maleate

PD-168077 maleate is a potent D4 dopamine receptor agonist (Ki = 8.7 nM), with > 400-fold and > 300-fold selectivity over D2 / D3 subtypes, respectively.

SCH23390

SCH23390 is a potent dopamine receptor antagonist (Ki values are 0.2 nM and 0.3 nM at D1 and D5 receptor sub-types, respectively).

MPTP HCl

MPTP hcl is a compound to the neurotoxin MPP+ which causes permanent symptoms of Parkinson's disease.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Sulpiride, Dolmatil, Dobren, Sulpyrid, Aiglonyl, Dogmatil supplier, Dopamine Receptor, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.