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Benztropine is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM. Benztropine mesylate is a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects. Benztropine mesylate is also an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate (Benzatropine mesylate) can be used for Parkinson's disease research.
| Molecular Weight | 403.53 |
| Formula | C21H25NO.CH4SO3 |
| CAS Number | 132-17-2 |
| Solubility (25°C) | DMSO 80 mg/mL Water 80 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] L A Baker, et al. The withdrawal of benztropine mesylate in chronic schizophrenic patients
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