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Amisulpride

Cat. No. M5410
Amisulpride Structure
Synonym:

DAN-2163

Size Price Availability Quantity
100mg USD 72  USD80 In stock
200mg USD 126  USD140 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 369.48
Formula C17H27N3O4S
CAS Number 71675-85-9
Purity >98%
Solubility 73 mg/mL in DMSO
Storage at -20°C
References

Prandial effect on the systemic exposure of amisulpride.
Jang YJ, et al. Arch Pharm Res. 2014 Oct;37(10):1325-8. PMID: 24469600.

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  Catalog
Abmole Inhibitor Catalog 2017




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