| Cat.No. | Name | Information |
|---|---|---|
| M5686 | Haloperidol | Haloperidol is a potent dopamine D2 receptor antagonist. |
| M9049 | MPTP HCl | MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease. |
| M2472 | Bromocriptine Mesylate | Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes. |
| M20535 | Chlorpromazine | Chlorpromazine is an orally active, blood-brain barrier-transparent D2 dopamine receptors and 5-HT2A antagonist. Chlorpromazine also blocks hNav1.7 channels (IC50=25.9 μM; concentration-dependent) and HERG potassium channels (IC50=21.6 μM). |
| M2494 | Cariprazine hydrochloride | Cariprazine hydrochloride is a dopamine D3-receptor-preferring partial agonist that exhibits high selectivity and affinity to dopamine D3 and D2(L/S) receptors with pKi 10.07 and 9.16/9.31, respectively. |
| M2445 | Benztropine mesylate | Benztropine is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM. Benztropine mesylate is a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects. Benztropine mesylate is also an anti-histamine agent and a dopamine re-uptake inhibitor. |
| M2415 | Azaperone | Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic compound with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine. |
| M2372 | Alizapride hydrochloride | Alizapride hydrochloride is a dopamine receptor antagonist used for the theropy of nausea and vomiting. |
| M1915 | Naxagolide | Naxagolide (Dopazinol) is a very potent and selective D2 agonist. |
| M1910 | Nepicastat hydrochloride | Nepicastat hydrochloride is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively. |
| M54825 | SV 156 | SV 156 is a potent and selective D2 dopamine receptor antagonist, with a Ki of 2.5 nM for hD2. SV 156 has approximately 40-fold binding selectivity for D2 dopamine receptors compared to the D3 receptor subtype. |
| M53201 | Cyclo(glycyl-L-leucyl) | Cyclo(glycyl-L-leucyl) (Cyclo(leu-gly)), a neuropeptide, down-regulates dopamine (DA) receptors and attenuates dopaminergic supersensitivity. |
| M53200 | Onzigolide | Onzigolide (BIM-23A760), a chimeric dopamine-somatostatin compound, shows potent agonist activity at both DA type 2 (D2R) and SST type 2 (SSTR2) receptors. |
| M49419 | CVL-871 | CVL-871 is a partial agonist at dopamine D1/5 receptors and may be used in dementia-related studies. |
| M45359 | Melevodopa | Melevodopaa is an oral precursor compound to Levodopa that enters the body and can pass through the gut and blood-brain barrier into the brain. In the brain, Melevodopa is converted to dopamine, which increases dopamine levels in the brain and can be used in studies related to Parkinson's disease. |
| M44845 | D-Tetrahydropalmatine | D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis. |
| M42176 | Ensaculin free base | Ensaculin free base (KA-672) is a NMDA antagonist and have high affinities to serotonergic 5-HT1A and 5-HT7 receptors, adrenergic α1, and dopaminergic D2 and D3 receptors. |
| M41815 | NPEC-caged-dopamine | NPEC-caged-dopamine is a caged version of dopamine. |
| M41814 | D4R agonist-1 | D4R agonist-1 is a D4R partial agonist (Ki: 2.2 nM). |
| M41813 | SKF 83822 | SKF 83822 is an atypical agonist of dopamine D1 receptor. |
| M41812 | SKF-75670 hydrobromide | SKF-75670 hydrochloride is a Dopamine D1 receptor partial agonist. |
| M41811 | GBR-12879 dihydrochloride | GBR-12879 dihydrochloride is a potent inhibitor of dopamine uptake. |
| M41810 | D3R/MOR antagonist 2 | D3R/MOR antagonist 2 is a D3R/MOR antagonist (Ki: 361 nM and 85.2 nM respectively). |
| M41809 | D3R/MOR antagonist 1 | D3R/MOR antagonist 1 is a D3R/MOR antagonist (Ki: 46.5 nM and 691 nM respectively). |
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