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Dopamine Receptor Dopamine Receptor

Cat.No.  Name Information
M5686 Haloperidol Haloperidol is a potent dopamine D2 receptor antagonist.
M9049 MPTP HCl MPTP is dehydrogenated in nigrostriatal cells to generate MPP+, which in turn inhibits mitochondrial complex enzymes and contributes to cell death. It can be used to construct animal models of Parkinson's disease.
M2472 Bromocriptine Mesylate Bromocriptine, an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.
M45359 Melevodopa Melevodopaa is an oral precursor compound to Levodopa that enters the body and can pass through the gut and blood-brain barrier into the brain. In the brain, Melevodopa is converted to dopamine, which increases dopamine levels in the brain and can be used in studies related to Parkinson's disease.
M44845 D-Tetrahydropalmatine D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis.
M42176 Ensaculin free base Ensaculin free base (KA-672) is a NMDA antagonist and have high affinities to serotonergic 5-HT1A and 5-HT7 receptors, adrenergic α1, and dopaminergic D2 and D3 receptors.
M41815 NPEC-caged-dopamine NPEC-caged-dopamine is a caged version of dopamine.
M41814 D4R agonist-1 D4R agonist-1 is a D4R partial agonist (Ki: 2.2 nM).
M41813 SKF 83822 SKF 83822 is an atypical agonist of dopamine D1 receptor.
M41812 SKF-75670 hydrobromide SKF-75670 hydrochloride is a Dopamine D1 receptor partial agonist.
M41811 GBR-12879 dihydrochloride GBR-12879 dihydrochloride is a potent inhibitor of dopamine uptake.
M41810 D3R/MOR antagonist 2 D3R/MOR antagonist 2 is a D3R/MOR antagonist (Ki: 361 nM and 85.2 nM respectively).
M41809 D3R/MOR antagonist 1 D3R/MOR antagonist 1 is a D3R/MOR antagonist (Ki: 46.5 nM and 691 nM respectively).
M41808 Bulbocapnine hydrochloride Bulbocapnine hydrochloride, an aporphine alkaloid, is a dopamine receptor inhibitor.
M41807 PNU-177864 PNU-177864 is a potent, selective and orally active dopamine D3 receptor antagonist.
M41806 FGH31 FGH31 is a potent, selective, GRK2 dependency dopamine D4 agonist, with the Ki of 1.6 nM.
M41805 D1R antagonist 1 D1R antagonist 1 is a D1R antagonist, involved in G-protein- and β-arrestin-based signaling.
M41804 Preclamol hydrochloride Preclamol hydrochloride ((-)-3-PPP hydrochloride) is a selective dopamine autoreceptor agonist.
M41803 D3R ligand 1 D3R ligand 1 is a potent and selective ligand of dopamine receptor D3R (Ki=66 nM), containing a THPB template.
M41802 Zuclopenthixol dihydrochloride Zuclopenthixol ((Z)-Clopenthixol) dihydrochloride is a thioxanthene derivative which acts as a mixed dopamine D1/D2 receptor antagonist.
M40719 UNC9995 UNC9995 is a novel β-arrestin 2-biased dopamine receptor Drd2 agonist that interferes with the assembly of inflammatory vesicles by enhancing the interaction of β-arrestin2 with NLRP3, thereby reducing IL-1β production.
M38957 Mulberrofuran H Mulberrofuran H demonstrates potent inhibition against substrates L-tyrosine (IC50=4.45 µM) and L-DOPA (IC50=19.70 µM). Mulberrofuran H also shows potent anti-inflammatory and antioxidative activities.
M30989 SKF-83566  SKF-83566 is a potent, blood-brain permeable and orally active D1-like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5-HT2 receptor (Ki=11 nM). SKF-83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5.7 μM. SKF-83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta. SKF-83566 can be used for research of parkinson’s disease and nicotine craving alleviation.




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