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Mesdopetam

Cat. No. M28345

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Mesdopetam Structure
Synonym:

IRL790

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Quality Control & Documentation
Biological Activity

Mesdopetam (IRL790) is a dopamine D3 receptor antagonist (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor) with psychomotor stabilizing properties. Mesdopetam is used for the research of motor and psychiatric complications in Parkinson disease.

Chemical Information
Molecular Weight 275.34
Formula C12H18FNO3S
CAS Number 1403894-72-3
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] M Angela Cenci, et al. Neuropharmacology. Non-dopaminergic approaches to the treatment of motor complications in Parkinson's disease

[2] Folke Sjöberg, et al. Pharmacol Res Perspect. A first-in-human oral dose study of mesdopetam (IRL790) to assess its safety, tolerability, and pharmacokinetics in healthy male volunteers

[3] Susanna Waters, et al. J Pharmacol Exp Ther. Preclinical Pharmacology of [2-(3-Fluoro-5-Methanesulfonyl-phenoxy)Ethyl](Propyl)amine (IRL790), a Novel Dopamine Transmission Modulator for the Treatment of Motor and Psychiatric Complications in Parkinson Disease

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Keywords: Mesdopetam, IRL790 supplier, Dopamine Receptor, inhibitors, activators

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