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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M4808 | TRV130 hydrochloride | TRV130 hydrochloride (Oliceridine) is a novel μ-opioid receptor (MOR) G protein-biased ligand. |
| M5067 | Eluxadoline | Eluxadoline is an orally active mixed μ opioid receptor (μOR) agonist δ opioid receptor (δOR) antagonist. |
| M5065 | Cebranopadol | Cebranopadol is a novel first in class compounds with potent agonist activity on ORL-1 (opioid receptor like -1) and the well established mu opioid receptor. |
| M4808 | TRV130 hydrochloride | TRV130 hydrochloride (Oliceridine) is a novel μ-opioid receptor (MOR) G protein-biased ligand. |
| M4456 | Sec-O-Glucosylhamaudol | Sec-o-glucosylhamaudol is a natural product isolated from The apostrophophore, which can reduce the protein level of μ-opioid receptor and can be used for pain relief research. |
| M3582 | Racecadotril | Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 μM |
| M2991 | SA 4503 | SA 4503 is a novel and selective opioid sigma1 receptor agonist with IC50 of 17.4 nM. |
| M2876 | Naloxone hydrochloride | Naloxone hydrochloride is an opioid inverse agonist compound used to counter the effects of opiate overdose. |
| M2214 | JTC-801 | JTC-801 is a novel opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM. |
| M2145 | Loperamide hydrochloride | Loperamide hydrochloride is a high affinity μ-opioid receptor agonist with peripheral selectivity with Ki values of 2, 48 and 1156 nM for μ-, δ- and κ-opioid receptors respectively. |
| M1953 | ADL5859 Hydrochloride | ADL5859 is a potent, selective and orally bioavailable δ-opioid receptor agonist (Ki = 0.84 nM, EC50 = 20 nM). |
| M1577 | Naltrexone Hydrochloride | Naltrexone hydrochlorideis an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. |
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