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SNC 80 is a highly selective non-peptide δ-opioid receptor agonist with a Ki of 1.78 nM and an IC50 of 2.73 nM, 2000-fold selective over μ-opioid receptors. SNC80 also selectively activates μ-δ heteromer in HEK293 cells with an EC50 of 52.8 nM. SNC80 shows antinociceptive, antihyperalgesic and antidepressant‐like effects. SNC80 (10 mg/kg; intraperitoneal injection; once) treatment significantly attenuated this allodynia caused by overuse of Sumatriptan in C57BL6/J mice.
| Molecular Weight | 449.64 |
| Formula | C28H39N3O2 |
| CAS Number | 156727-74-1 |
| Solubility (25°C) | DMSO 30 mg/mL 1eq. HCl 40 mg/mL (with gentle warming) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Opioid Receptor Products |
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SCH 486757 is an orally effective pain peptide receptor (NOP) agonist. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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