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DAMGO is an opioid receptor agonist with the ability to affect the locomotive activity in rodents, Kd value is 3.46 nM for native μ-OPR. DAMGO abolishes the neuroprotective effect of CXCL12 in N-methyl-d-aspartate (NMDA) neurotoxicity studies.
Eur J Pharmacol. 2024 Mar 5;966:176333.
The μ-opioid receptor-mediated Gi/o protein and β-arrestin2 signaling pathways both contribute to morphine-induced side effects
DAMGO purchased from AbMole
Tetrahedron Letters. 2022 Dec 7.
Gram-scale preparation of DAMGO by typical solid phase synthesis
DAMGO purchased from AbMole
| Molecular Weight | 513.59 |
| Formula | C26H35N5O6 |
| CAS Number | 78123-71-4 |
| Solubility (25°C) | DMSO ≥ 21 mg/mL |
| Storage | -20°C, protect from light, dry, sealed |
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