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Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist. Dynorphin A (1-13) exposure (33 μM) causes a significant loss in neuronal viability at 4 h with a visible destruction in neuronal morphology seen at 16 h. Exposure to dynorphin A (1-13) causes acute increases in [Ca 2+ ] i in individual neurons similar to increases seen with acute NMDA treatment. Continuous exposure to dynorphin A (1-13) (100 μM) causes a significant loss of neurons over time.
| Molecular Weight | 1603.95 |
| Formula | C75H126N24O15 |
| CAS Number | 72957-38-1 |
| Solubility (25°C) | Water 60 mg/mL |
| Storage | -20°C, sealed |
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