About 30 results found for searched term "m-Se3" (0.027 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6080 | Elimusertib (BAY-1895344) | ATM/ATR |
| Elimusertib | ||
| Elimusertib (BAY-1895344) is an effective, oral, selective ATR inhibitor with an IC50 value of 7 nM and antitumor activity. Elimusertib (Bay-1895344) showed antitumor activity against A2780 ovarian cancer, PC-3 prostate cancer, LOVO colorectal cancer and REC-1 suite cell lymphoma, and was most sensitive to lymphoma. | ||
| M8100 | PF06650833 (Zimlovisertib) | IRAK |
| Zimlovisertib; PF 6650833 | ||
| PF06650833 (Zimlovisertib) is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4). | ||
| M10020 | Recombinant Mouse TPO Protein (HEK293) | Recombinant Proteins |
| Thrombopoietin; THPO | ||
| Recombinant Mouse TPO protein (HEK293) is a lineage-specific growth factor produced in the liver, kidney, and skeletal muscle, stimulates the proliferation and maturation of megakaryocytes and promotes the increase of platelet circulation in the body. | ||
| M10021 | Recombinant Mouse BMP-4 Protein (HEK293, rFc Tag) | Recombinant Proteins |
| Bmp-4 Protein Mouse | ||
| Recombinant Mouse BMP-4 Protein is a TGF-beta superfamily ligand that is widely expressed from early embryogenesis through adulthood. | ||
| M10115 | Recombinant Mouse TNF-α Protein (HEK293) | Recombinant Proteins |
| TNFSF2 | ||
| TNF-α (HEK293) is a pleiotropic pro-inflammatory cytokine secreted by a variety of cells such as adipocytes, activated monocytes, macrophages, B cells, T cells, and fibroblasts. | ||
| M11017 | Camonsertib (RP-3500) | ATM/ATR |
| ATR inhibitor 4; Camonsertib | ||
| Camonsertib (RP-3500) is an orally potent, selective ATR kinase inhibitor (ATRi) in biochemical assays IC50 1.00 nM. The RP-3500 is 30 times more selective to ATR (IC).50=120 nM), which is 2,000 times > ATM, DNA-PK, and PI3Kα kinase. | ||
| M11197 | Recombinant Mouse IL-13 Protein (CHO, His) | Recombinant Proteins |
| rMuIL-13, His; P600 | ||
| Recombinant Mouse IL-13 Protein (CHO, His) is an important cytokine derived from CHO cells, a multifunctional cytokine whose main role is to reduce the inflammatory response. | ||
| M11491 | Recombinant Mouse IL-33 (E. coli, 98%) | Recombinant Proteins |
| IL33; C9orf26; DVS27; IL1F11 | ||
| Interleukin-33 (IL-33) is a proinflammatory cytokine that belongs to the IL-1 family. IL-33 is expressed in a variety of cells, including epithelial and endothelial cells, smooth muscle cells, macrophages and fibroblasts. The ED50 measured by D10S cell proliferation assay was less than 0.5 ng/ mL, corresponding to a specific activity of > 2.0 × 106IU/mg. | ||
| M13442 | Recombinant Mouse IL-36 gamma (E.coli) | Recombinant Proteins |
| IL-36 gamma（E.coli） | ||
| Recombinant mouse IL-36 γ is produced by our EScherichia coli expression system and expresses the target gene encoding Gly13-Ser164. | ||
| M13443 | Recombinant Mouse IL-36 alpha (E.coli) | Recombinant Proteins |
| IL-36 alpha (E.coli) | ||
| The recombinant mouse interleukin-36 α was produced by escherichia coli expression system and the target gene encoding ARG8-HIS160 was expressed. | ||
| M13444 | Recombinant Mouse IL-36 beta (E.coli) | Recombinant Proteins |
| IL-36 beta (E.coli) | ||
| Recombinant mouse interleukin-36 β is produced by the escherichia coli expression system and the target gene encoding Ser31-Lys183 is expressed. | ||
| M15025 | Recombinant Mouse MIP-1α/CCL3 (HEK 293) | Recombinant Proteins |
| Macrophage Inflammatory Protein-1α; CCL-3; LD78α; LD78 alpha | ||
| MIP-1 Alpha, also known as CCL3, G0S19-1 and SCYA3, LD78 Alpha, is an inflammatory chemokine. Mip-1 α belongs to the CCL chemokine family and has 68% homology with MIP-1β. The mature form of MIP-1α contains 69 amino acids, which are present in solution as dimers and tend to accumulate reversibly. Protein structure: MIP-1α (ALA24-ALA92), Accession # : Q5QNW0. | ||
| M15029 | Recombinant Mouse CT-1 (HEK 293) | Recombinant Proteins |
| CTF1; CT-1 | ||
| Cardiac trophin-1 (CT-1) is a member of the cytokine family, which also includes IL-6, IL-11, leukemia suppressor (LIF), tumor suppressor M (OSM), and ciliary neurotrophin (CNTF). Protein structure: CT-1 (SER2-ALA203), Accession # Q60753-1. | ||
| M15054 | Recombinant Mouse DCIP-1/CXCL3 (CHO) | Recombinant Proteins |
| C-X-C motif chemokine 3; Dendritic cell inflammatory protein 1 | ||
| Chemokine (C-X-C Motif) ligand 3 (CXCL3) is a small cytokine in the CXC chemokine family, also known as DCIP-1(Dendritic cell inflammatory protein-1) or MIP-2B. Protein structure: CXCL3 (ALA28-SER100), Accession # : Q6W5C0. | ||
| M15055 | Recombinant Mouse DCIP-1/CXCL3 (E. coli) | Recombinant Proteins |
| C-X-C motif chemokine 3; Dendritic cell inflammatory protein 1 | ||
| Dendritic cell inflammatory protein-1 (DCIP-1)/CXCL3 is also known as MIP2β(macrophage inflammatory protein 2 beta) or DCIP1(Dendritic cell inflammatory protein 1) in mice and CINC2(cytodynamics-induced neutrophil attractant 2) in rats, In humans it is known as GRO gamma (Growth regulated oncogene gamma). Biological structure: CXCL3 (ALA28-SER100), Accession # : Q6W5C0. | ||
| M15047 | Recombinant Mouse OSM (HEK 293) | Recombinant Proteins |
| OncoM; oncostatin M | ||
| Protein Construction：OSM (Ala24-Arg206) Oncostatin M (OSM) is a multifunctional cytokine belonging to the interleukin-6 (IL-6) subfamily, which also includes IL-11, leukemia suppressor (LIF), ciliary nerve promoter, cardiac trophic factor-1 and novel nerve promoter factor-1. Protein structure: OSM (ALA24-ARG206), Accession # : P53347. | ||
| M19980 | Recombinant Mouse MIP-3α/CCL20 (E. coli) | Recombinant Proteins |
| CCL-20; CKb4; Exodus; LARC; MIP-3-alpha | ||
| Macrophage Inflammatory Protein-3 (MIP-3α), also known as chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC), is a small cytokine belonging to the CC chemokine family. Determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells, the biologically active is in a concentration range of 0.1-10.0 ng/ml. | ||
| M19995 | Recombinant Human/Mouse/Rat TGF-β3 (Mammalian) | Recombinant Proteins |
| Transforming growth factor beta-3; TGFB3 | ||
| Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is involved incell differentiation, embryogenesis and development. It regulates molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. | ||
| M20626 | Amcasertib (BBI503) | Others |
| Amcasertib (BBI-503) is an oral first-in-class cancer stemness kinase inhibitor. By targeting multiple serine-threonine stemness kinases, amcasertib inhibits Nanog and other cancer stemness pathways. | ||
| M20983 | Barnidipine | Calcium Channel |
| Libradin, Mepirodipine, Vasexten, YM-09730-5, Cyress, Hypoca, Oldeca | ||
| Barnidipine (Libradin, Mepirodipine, Vasexten, YM-09730-5, Cyress, Hypoca, Oldeca) is an antihypertensive drug that belongs to the dihydropyridine (DHP) group of calcium antagonist (CaA) with Ki of 0.21 nM for [3H]nitrendipine binding sites. | ||
| M21210 | Recombinant Mouse IL-3 (E. coli) | Recombinant Proteins |
| IL3; interleukin 3; IL-3; MCGF | ||
| ED50 < 0.05 ng/ml, measured by cell proliferation assay using M-NFS-60 cells, corresponds to specific activity > 2.0 × 10 7 units/mg. Accession # P01586. | ||
| M21354 | Recombinant Human SEMA3E (E. coli, N-His) | Recombinant Proteins |
| SEMAH, Semaphorin-3E, SEMA3E, KIAA0331 | ||
| Protein Construct: DNA sequence encoding human SEMA3E (Arg32-Phe516) fused to an N-His tag. accession #: O15041. | ||
| M21546 | Recombinant Mouse IL-3 (E. coli, C-6His) | Recombinant Proteins |
| IL3; interleukin 3; IL-3; MCGF; MULTI-CSF; Mast cell growth factor | ||
| Interleukin-3 (IL-3) is a multipotent cytokine belonging to the interleukin-family. Biological activity: ED50 < 0.05 ng/ml was determined by M-NFS-60 cell proliferation method, and the corresponding specific activity was 2.0 × 10 7 units /mg. | ||
| M21612 | Recombinant Mouse IFN-beta Protein (HEK293) | Recombinant Proteins |
| IFN-beta; IFNB Protein | ||
| Interferon-beta (IFN beta) is an extracellular protein mediator of host defense and homeostasis. IFN beta has well-established direct antiviral, antiproliferative, and immunomodulatory properties. Recombinant IFN beta is approved for the treatment of relapsing-remitting multiple sclerosis. Measured in antiviral assays using L929 cells infected with vesicular stomatitisvirus (VSV). The ED50 for this effect is 3-18 pg/mL. | ||
| M21670 | Recombinant Mouse/Rat VEGF-C Protein (HEK293, aa 108-223, Fc Tag) | Recombinant Proteins |
| Vascular endothelial growth factor C | ||
| Recombinant Mouse/Rat VEGF-C Protein is a dimeric glycoprotein, as a ligand for two receptors, VEGFR-3 (Flt4), and VEGFR-2. VEGF-C may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis. Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC), the ED50 is typically 70-300 ng/mL. | ||
| M21671 | Recombinant Mouse/Rat VEGF-C Protein (HEK293, aa 108-223, His Tag) | Recombinant Proteins |
| Vascular endothelial growth factor C | ||
| Recombinant Mouse/Rat VEGF-C Protein is a dimeric glycoprotein, as a ligand for two receptors, VEGFR-3 (Flt4), and VEGFR-2. VEGF-C may function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis. Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC), the ED50 for this effect is typically 0.1-0.8 μg/mL. | ||
| M21679 | Recombinant Mouse IL-23 (Mammalian) | Recombinant Proteins |
| Interleukin-23 | ||
| Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. Recombinant Mouse Interleukin-23 is produced by Mammalian expression system and the target gene encoding Val22-Ala196&Met23-Ser335 is expressed. | ||
| M21684 | Recombinant Human MMP-3 (Mammalian, C-6His) | Recombinant Proteins |
| Matrix metalloproteinase-3 | ||
| MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes. Recombinant Human Matrix Metalloproteinase-3 is produced by Mammalian expression system and the target gene encoding Tyr18-Cys477 is expressed with a 6His tag at the C-terminus.The proenzyme needs to be activated by Chymotrypsin for an activated form. | ||
| M21703 | Recombinant Mouse Angiopoietin-1 Protein (HEK293, His Tag) | Recombinant Proteins |
| Ang-1 Protein, Mouse | ||
| Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. | ||
| M21707 | Recombinant Mouse HSP70 Protein (HEK293, His Tag) | Recombinant Proteins |
| HSPA1A; heat shock 70kDa protein 1A | ||
| HSPA1A is a member of the Hsp70 protein family. The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. The Hsp70 family stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. | ||
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