About 30 results found for searched term "m-Se3" (0.024 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6080 | Elimusertib (BAY-1895344) | ATM/ATR |
| Elimusertib | ||
| Elimusertib (BAY-1895344) is an effective, oral, selective ATR inhibitor with an IC50 value of 7 nM and antitumor activity. Elimusertib (Bay-1895344) showed antitumor activity against A2780 ovarian cancer, PC-3 prostate cancer, LOVO colorectal cancer and REC-1 suite cell lymphoma, and was most sensitive to lymphoma. | ||
| M8100 | PF06650833 (Zimlovisertib) | IRAK |
| Zimlovisertib; PF 6650833 | ||
| PF06650833 (Zimlovisertib) is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4). | ||
| M10020 | Recombinant Mouse TPO Protein (HEK293) | Cytokines and Growth Factors |
| Thrombopoietin; THPO | ||
| Recombinant Mouse TPO protein (HEK293) is a lineage-specific growth factor produced in the liver, kidney, and skeletal muscle, stimulates the proliferation and maturation of megakaryocytes and promotes the increase of platelet circulation in the body. | ||
| M10021 | Recombinant Mouse BMP-4 Protein (HEK293, rFc Tag) | Cytokines and Growth Factors |
| Bmp-4 Protein Mouse | ||
| Recombinant Mouse BMP-4 Protein is a TGF-beta superfamily ligand that is widely expressed from early embryogenesis through adulthood. | ||
| M10115 | Recombinant Mouse TNF-α Protein (HEK293) | Cytokines and Growth Factors |
| TNFSF2 | ||
| TNF-α (HEK293) is a pleiotropic pro-inflammatory cytokine secreted by a variety of cells such as adipocytes, activated monocytes, macrophages, B cells, T cells, and fibroblasts. | ||
| M11017 | Camonsertib (RP-3500) | ATM/ATR |
| ATR inhibitor 4; Camonsertib | ||
| Camonsertib (RP-3500) is an orally potent, selective ATR kinase inhibitor (ATRi) in biochemical assays IC50 1.00 nM. The RP-3500 is 30 times more selective to ATR (IC).50=120 nM), which is 2,000 times > ATM, DNA-PK, and PI3Kα kinase. | ||
| M11197 | Recombinant Mouse IL-13 Protein (CHO, C-His) | Cytokines and Growth Factors |
| rMuIL-13, His; P600 | ||
| Recombinant Mouse IL-13 Protein is an immunoregulatory cytokine belonging to the IL-4/IL-13 family, a multifunctional cytokine whose main role is to reduce the inflammatory response. | ||
| M11491 | Recombinant Mouse IL-33 (E. coli, 98%) | Cytokines and Growth Factors |
| IL33; C9orf26; DVS27; IL1F11 | ||
| Interleukin-33 (IL-33) is a proinflammatory cytokine that belongs to the IL-1 family. IL-33 is expressed in a variety of cells, including epithelial and endothelial cells, smooth muscle cells, macrophages and fibroblasts. The ED50 measured by D10S cell proliferation assay was less than 0.5 ng/ mL, corresponding to a specific activity of > 2.0 × 106IU/mg. | ||
| M13442 | Recombinant Mouse IL-36 gamma (E.coli) | Cytokines and Growth Factors |
| IL-36 gamma（E.coli） | ||
| Recombinant mouse IL-36 γ is produced by our EScherichia coli expression system and expresses the target gene encoding Gly13-Ser164. | ||
| M13443 | Recombinant Mouse IL-36 alpha (E.coli) | Cytokines and Growth Factors |
| IL-36 alpha (E.coli) | ||
| The recombinant mouse interleukin-36 α was produced by escherichia coli expression system and the target gene encoding ARG8-HIS160 was expressed. | ||
| M13444 | Recombinant Mouse IL-36 beta (E.coli) | Cytokines and Growth Factors |
| IL-36 beta (E.coli) | ||
| Recombinant mouse interleukin-36 β is produced by the escherichia coli expression system and the target gene encoding Ser31-Lys183 is expressed. | ||
| M15025 | Recombinant Mouse MIP-1α/CCL3 (HEK 293) | Cytokines and Growth Factors |
| Macrophage Inflammatory Protein-1α; CCL-3; LD78α; LD78 alpha | ||
| MIP-1 Alpha, also known as CCL3, G0S19-1 and SCYA3, LD78 Alpha, is an inflammatory chemokine. Mip-1 α belongs to the CCL chemokine family and has 68% homology with MIP-1β. The mature form of MIP-1α contains 69 amino acids, which are present in solution as dimers and tend to accumulate reversibly. Protein structure: MIP-1α (ALA24-ALA92), Accession # : Q5QNW0. | ||
| M15029 | Recombinant Mouse CT-1 (HEK 293) | Cytokines and Growth Factors |
| CTF1; CT-1 | ||
| Cardiac trophin-1 (CT-1) is a member of the cytokine family, which also includes IL-6, IL-11, leukemia suppressor (LIF), tumor suppressor M (OSM), and ciliary neurotrophin (CNTF). Protein structure: CT-1 (SER2-ALA203), Accession # Q60753-1. | ||
| M15054 | Recombinant Mouse DCIP-1/CXCL3 (CHO) | Cytokines and Growth Factors |
| C-X-C motif chemokine 3; Dendritic cell inflammatory protein 1 | ||
| Chemokine (C-X-C Motif) ligand 3 (CXCL3) is a small cytokine in the CXC chemokine family, also known as DCIP-1(Dendritic cell inflammatory protein-1) or MIP-2B. Protein structure: CXCL3 (ALA28-SER100), Accession # : Q6W5C0. | ||
| M15046 | Recombinant Human/Mouse/Rat Activin A (HEK293) | Cytokines and Growth Factors |
| Inhibin beta A chain;INHBA;Activin A | ||
| Recombinant human/mouse/rat Activin A protein is a multifunctional cytokine belonging to transforming growth factor β (TGF β) superfamily. It is associated with a variety of pathophysiological processes, including inflammation, fibrosis, and tumorigenesis. | ||
| M15055 | Recombinant Mouse CXCL3 (E. coli, His Tag) | Cytokines and Growth Factors |
| C-X-C motif chemokine 3; Dendritic cell inflammatory protein 1; DCIP-1 | ||
| Dendritic cell inflammatory protein-1 (DCIP-1)/CXCL3 is also known as MIP2β(macrophage inflammatory protein 2 beta) or DCIP1(Dendritic cell inflammatory protein 1) in mice and CINC2(cytodynamics-induced neutrophil attractant 2) in rats, In humans it is known as GRO gamma (Growth regulated oncogene gamma). | ||
| M15047 | Recombinant Mouse OSM (HEK 293) | Cytokines and Growth Factors |
| OncoM; oncostatin M | ||
| Protein Construction：OSM (Ala24-Arg206) Oncostatin M (OSM) is a multifunctional cytokine belonging to the interleukin-6 (IL-6) subfamily, which also includes IL-11, leukemia suppressor (LIF), ciliary nerve promoter, cardiac trophic factor-1 and novel nerve promoter factor-1. Protein structure: OSM (ALA24-ARG206), Accession # : P53347. | ||
| M15014 | Recombinant Human Carboxypeptidase M (HEK293,C-6His) | Cytokines and Growth Factors |
| Carboxypeptidase M;CPM | ||
| Carboxypeptidase M (CPM) plays important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins. It is widely distributed in a variety of tissues and cells. | ||
| M15008 | Recombinant Human Carboxypeptidase E/CPE (HEK293,C-6His) | Cytokines and Growth Factors |
| Carboxypeptidase H; Enkephalin convertase | ||
| CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. | ||
| M15076 | Recombinant Mouse HGF (HEK293,C-6His) | Cytokines and Growth Factors |
| Hepatopoietin-A;Scatter factor;SF;deafness, autosomal recessive 39 | ||
| Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. | ||
| M15078 | Recombinant Mouse Noggin/NOG (HEK293,C-6His) | Cytokines and Growth Factors |
| Noggin; Nog | ||
| Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Noggin binds some BMPs such as BMP4 with high affinity and others such as BMP7 with lower affinity. It antagonizes BMP bioactivities by blocking epitopes on BMPs that are needed for binding to both type I and type II receptors. Accession # : P97466. | ||
| M15095 | Recombinant Mouse RANKL (HEK293, N-6His) | Cytokines and Growth Factors |
| Tnfsf11 | ||
| Recombinant Mouse RANKL/TNFSF11 is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation. | ||
| M19980 | Recombinant Mouse MIP-3α/CCL20 (E. coli) | Cytokines and Growth Factors |
| CCL-20; CKb4; Exodus; LARC; MIP-3-alpha | ||
| Macrophage Inflammatory Protein-3 (MIP-3α), also known as chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC), is a small cytokine belonging to the CC chemokine family. Determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells, the biologically active is in a concentration range of 0.1-10.0 ng/ml. | ||
| M19995 | Recombinant Human/Mouse/Rat TGF-β3 (HEK293) | Cytokines and Growth Factors |
| Transforming growth factor beta-3; TGFB3 | ||
| Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is involved incell differentiation, embryogenesis and development. It regulates molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development. | ||
| M20626 | Amcasertib (BBI503) | Others |
| Amcasertib (BBI-503) is an oral first-in-class cancer stemness kinase inhibitor. By targeting multiple serine-threonine stemness kinases, amcasertib inhibits Nanog and other cancer stemness pathways. | ||
| M20983 | Barnidipine | Calcium Channel |
| Libradin, Mepirodipine, Vasexten, YM-09730-5, Cyress, Hypoca, Oldeca | ||
| Barnidipine (Libradin, Mepirodipine, Vasexten, YM-09730-5, Cyress, Hypoca, Oldeca) is an antihypertensive drug that belongs to the dihydropyridine (DHP) group of calcium antagonist (CaA) with Ki of 0.21 nM for [3H]nitrendipine binding sites. | ||
| M21201 | Recombinant Mouse Lipocalin-2/NGAL Protein (HEK293, C-6His) | Cytokines and Growth Factors |
| Neutrophil gelatinase-associated lipocalin; LCN2 | ||
| Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 can tightly bind to bacterial siderophore through a cell surface receptor, possibly serving as a potent bacteriostatic agent by sequestering iron, regulating innate immunity and protecting kidney epithelial cells from ischemia–reperfusion injury. | ||
| M21203 | Recombinant Human/Mouse/Rat Irisin (HEK293, C-6His) | Cytokines and Growth Factors |
| Fibronectin type III domain-containing protein 5 | ||
| Fibronectin type III domain-containing protein 5 is the precursor of irisin. Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor γ coactivator 1α (PGC1α) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into more metabolically active beige adipose tissue.Irisin also regulates neuronal cell differentiation and neurite outgrowth in the brain and is involved in the differentiation of osteoblasts. | ||
| M21204 | Recombinant Human/Mouse/Rat Irisin (HEK293, C-Fc) | Cytokines and Growth Factors |
| Fibronectin type III domain-containing protein 5 | ||
| Fibronectin type III domain-containing protein 5 is the precursor of irisin. Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor γ coactivator 1α (PGC1α) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into more metabolically active beige adipose tissue.Irisin also regulates neuronal cell differentiation and neurite outgrowth in the brain and is involved in the differentiation of osteoblasts. | ||
| M21205 | Recombinant Human/Mouse/Rat Irisin (HEK293, N-6His) | Cytokines and Growth Factors |
| Fibronectin type III domain-containing protein 5 | ||
| Fibronectin type III domain-containing protein 5 is the precursor of irisin. Mature human, mouse share 100% sequence identity.Irisin induces expression of peroxisome proliferatoractivated receptor γ coactivator 1α (PGC1α) and uncoupling protein1(UCP1), mitochondrialassociated metabolic proteins. Irisin induces the transition of white adipose tissue into more metabolically active beige adipose tissue.Irisin also regulates neuronal cell differentiation and neurite outgrowth in the brain and is involved in the differentiation of osteoblasts. | ||
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