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Recombinant Human/Mouse/Rat Activin A (HEK293)

Cat. No. M15046

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human/Mouse/Rat Activin A (HEK293) Structure
Synonym:

Inhibin beta A chain;INHBA;Activin A

Size Price Availability Quantity
10ug USD 300  USD300 In stock
50ug USD 710  USD710 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 0.01 EU/µg
  • COA
  • MSDS
Biological Activity

Recombinant human/mouse/rat Activin A protein is A multifunctional cytokine belonging to transforming growth factor β (TGF β) superfamily. It is associated with a variety of pathophysiological processes, including inflammation, fibrosis, and tumorigenesis.

Measured by its ability to induce SMAD signaling in 293-Activin A Res cells, the ED50 for this effect is 1.3 ng/ml.

Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells, the ED50 for this effect is ~1.2 ng/mL.


Accession: P08476

Endotoxin < 0.01 EU/µg

Apparent Molecular Weight: 14-15 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of 4mM HCl.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at ≤ -20°C for 3 months.
References

[1] Elisabeth Nadjar-Boger, et al. Biol Bull. Two Activin Type 2B Receptors from Sea Bream Function Similarly in vitro

[2] C Joy McIntosh, et al. Biol Reprod. The proregion of mouse BMP15 regulates the cooperative interactions of BMP15 and GDF9

[3] Noora Kaivo-Oja, et al. J Clin Endocrinol Metab. Growth differentiation factor-9 induces Smad2 activation and inhibin B production in cultured human granulosa-luteal cells

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Keywords: Recombinant Human/Mouse/Rat Activin A (HEK293), Inhibin beta A chain;INHBA;Activin A supplier, Cytokines and Growth Factors, inhibitors, activators

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