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Recombinant Human/Mouse/Rat TGF-β3 (Mammalian)

Cat. No. M19995

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Human/Mouse/Rat TGF-β3 (Mammalian) Structure
Synonym:

Transforming growth factor beta-3; TGFB3

Size Price Availability Quantity
10ug USD 280  USD280 In stock
50ug USD 800  USD800 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 0.01 EU/µg
  • COA
  • MSDS
Biological Activity

Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development. It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development.

Recombinant Human/Mouse/Rat Transforming Growth Factor Beta 3 expressed the target gene encoding Ala301-Ser412(Tyr340Phe).

Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T cells, the ED50 for this effect is 10-80 pg/ml.


Accession: P10600

Endotoxin < 0.01 EU/µg

Apparent Molecular Weight: 12-14 KDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl, 150mM NaCl, pH 2.5.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
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Keywords: Recombinant Human/Mouse/Rat TGF-β3 (Mammalian), Transforming growth factor beta-3; TGFB3 supplier, Recombinant Proteins, inhibitors, activators

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