All AbMole products are for research use only, cannot be used for human consumption.
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development. It is believed to regulate molecules involved in cellularadhesion and extracellular matrix (ECM) formation during the process of palate development.
Recombinant Human/Mouse/Rat Transforming Growth Factor Beta 3 expressed the target gene encoding Ala301-Ser412(Tyr340Phe).
Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 mouse T cells, the ED50 for this effect is 10-80 pg/ml.
Accession: P10600
Endotoxin < 0.01 EU/µg
Apparent Molecular Weight: 12-14 KDa, reducing conditions
Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl, 150mM NaCl, pH 2.5.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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