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Recombinant Mouse IL-13 Protein (CHO, C-His)

Cat. No. M11197

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse IL-13 Protein (CHO, C-His) Structure
Synonym:

rMuIL-13, His; P600

Size Price Availability Quantity
10ug USD 220  USD220 In stock
50ug USD 720  USD720 In stock
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Quality Control & Documentation
  • Purity: >95%, Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
Biological Activity

Recombinant Mouse IL-13 Protein is an immunoregulatory cytokine belonging to the IL-4/IL-13 family, a multifunctional cytokine whose main role is to reduce the inflammatory response. IL-13 signals through a receptor complex composed of IL-4Rα and IL13Rα1 (or IL13Rα2). IL-13 inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α and IL-6 by monocytes and macrophages. It also induces B cell activation and IgE secretion.

Recombinant Mouse IL-13 Protein expressed the target gene encoding Pro22-Phe131 with a polyhistidine tag at the C-terminus.

Measured in a cell proliferation assay using R&D TF-1 cells, the ED50 is < 20.0 ng /ml.


Accession: P20109

Endotoxin < 0.2 EU/µg

Apparent Molecular Weight: 14~30 kDa, reducing conditions

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Chemical Information
Form Lyophilized powder
Solubility (25°C) Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml.
Storage Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months.
References

[1] Sreeja Roy, et al. Sci Rep. Unique IL-13Rα2/STAT3 mediated IL-13 regulation detected in lung conventional dendritic cells, 24 h post viral vector vaccination

[2] Kai J Rogers, et al. PLoS Negl Trop Dis. IL-4/IL-13 polarization of macrophages enhances Ebola virus glycoprotein-dependent infection

[3] Dylan J Wodsedalek, et al. Am J Physiol Heart Circ Physiol. IL-13 promotes in vivo neonatal cardiomyocyte cell cycle activity and heart regeneration

[4] Akiko Suzuki, et al. Cytokine. Targeting of IL-4 and IL-13 receptors for cancer therapy

[5] Dong Li, et al. J Allergy Clin Immunol. IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice

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Keywords: Recombinant Mouse IL-13 Protein (CHO, C-His), rMuIL-13, His; P600 supplier, Cytokines and Growth Factors, inhibitors, activators

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