All AbMole products are for research use only, cannot be used for human consumption.
Mouse RANKL/TNFSF11 is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells, including T cells, and in T cell-rich organs, such as the thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG and TNFRSF11A /RANK. Tnfsf11 is involved in many fundamental biological processes, such as acting as a regulator of interactions between T cells and dendritic cells, regulating T cell-dependent immune responses and enhancing bone resorption in malignant humoral hypercalcemia. It enhances the ability of dendritic cells to stimulate the proliferation of naive T cells.
Loaded Recombinant Human OPG-Fc on Pro A Biosensor, can bind Mouse RANKL-His(M15095) with an affinity constant of 1.02 pM as determined in BLI assay.
Accession: BAA97257.1
APMol Mass: 30-35 KDa, reducing conditions
Endotoxin <1 EU/µg
Lyophilized from a 0.2 μm filtered solution of 20mM Hepes-NaOH, 50mM NaCl, 6% Trehalose, 4% Mannitol, 0.05% Tween 80, pH 8.0.
| Form | Lyophilized powder |
| Solubility (25°C) | Reconstitute the lyophilized powder in distilled water up to 100 μg/ml. |
| Storage | Stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days and at -20°C for 3 months. |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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