About 30 results found for searched term "Dopamine Receptor" (0.044 seconds)
Cat.No. | Name | Target |
---|---|---|
M2349 | (R)-Nepicastat hydrochloride | HCV Protease |
RS-25560-198 HCl | ||
(R)-Nepicastat hydrochloride, the R-enantiomer of Nepicastat hydrochloride, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. | ||
M2372 | Alizapride hydrochloride | Dopamine Receptor |
Alizapride hydrochloride is a dopamine receptor antagonist used for the theropy of nausea and vomiting. | ||
M2445 | Benztropine mesylate | Dopamine Receptor |
Benzatropine mesylate; Benzotropine mesylate; Benztropine methanesulfonate | ||
Benztropine is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM. Benztropine mesylate is a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects. Benztropine mesylate is also an anti-histamine agent and a dopamine re-uptake inhibitor. | ||
M2494 | Cariprazine hydrochloride | Dopamine Receptor |
RGH-188 HCl | ||
Cariprazine hydrochloride is a dopamine D3-receptor-preferring partial agonist that exhibits high selectivity and affinity to dopamine D3 and D2(L/S) receptors with pKi 10.07 and 9.16/9.31, respectively. | ||
M2655 | Droperidol | Dopamine Receptor |
Dehydrobenzperidol | ||
Droperidol is a potent antagonist of dopamine subtype 2 receptors in the limbic system. | ||
M2886 | Nomifensine Maleate | Dopamine Receptor |
(±)-Nomifensine maleat | ||
Nomifensine is a dopamine reuptake inhibitor that increases the amount of synaptic dopamine available to receptors by blocking dopamine's re-uptake transporter. | ||
M2925 | Pergolide mesylate | Dopamine Receptor |
LY127809 | ||
Pergolide mesylate is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for the research of Parkinson's disease and hyperprolactinaemia. | ||
M2936 | Phenothiazine | Dopamine Receptor |
Phenothiazine is a dopamine-2 (D2) receptor antagonist therefore decreases the effect of dopamine in the brain. | ||
M2987 | Ropinirole hydrochloride | Dopamine Receptor |
SKF 101468 hydrochloride | ||
Ropinirole a selective dopamine D2 receptors inhibitor with IC50 of 29 nM. | ||
M3065 | Thioridazine hydrochloride | Dopamine Receptor |
Thioridazine is a trifluoro-methyl phenothiazine derivative, which blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain. | ||
M3087 | Trifluoperazine dihydrochloride | Dopamine Receptor |
TFP; SKF5019 | ||
Trifluoperazine is a dopamine D2 receptor inhibitor with IC50 of 1.1 nM. | ||
M3088 | Triflupromazine hydrochloride | Dopamine Receptor |
Triflupromazine hydrochloride is a member of a family of phenothiazine compounds that are dopamine D1/D2 receptor antagonists. | ||
M3165 | Prochlorperazine dimaleate | Dopamine Receptor |
Prochlorperazine dimaleate is a D2 dopamine receptor antagonist. | ||
M3242 | Sumanirole Maleate | Dopamine Receptor |
U 95666E | ||
Sumanirole maleate is a highly selective dopamine D2 receptor agonist with binding affinity of 9 nM and EC50 of about 46 nM, exhibits >200-fold selectivity over the other dopamine receptor subtypes. | ||
M3287 | PD128907 hydrochloride | Dopamine Receptor |
PD 128907 hydrochloride is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor. | ||
M3320 | Quetiapine Fumarate | 5-HT Receptor |
Quetiapine hemifumarate | ||
Quetiapine hemifumarate is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. | ||
M3414 | Olanzapine | 5-HT Receptor |
LY170053 | ||
Olanzapine is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist. | ||
M3479 | Aripiprazole | 5-HT Receptor |
OPC-14597 | ||
Aripiprazole is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM. Aripiprazole (OPC-14597) is a potent and high-affinity dopamine D2 receptor partial agonist. | ||
M3481 | WAY-100635 Maleate | 5-HT Receptor |
WAY-100635 maleate is a potent, selective 5-HT1A receptor antagonist with an IC50 value of 0.91 nM, a Ki value of 0.39 nM, and a pIC50 of 8.87, which is more than 100-fold more selective than for use at the other 5-HT receptor subtypes and major neurotransmitter receptors. In addition, WAY-100635 maleate is a potent dopamine D4 receptor agonist. | ||
M3592 | Chlorprothixene | Dopamine Receptor |
Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively. | ||
M3670 | Metoclopramide hydrochloride | 5-HT Receptor |
Metoclopramide hydrochloride is a selective dopamine D2 receptor antagonist, used for the treatment of nausea and vomiting. | ||
M3674 | Metoclopramide | Dopamine Receptor |
Metoclopramide is a potent antagonist of 5-HT3 and dopamine D2 receptor, with IC50s of 308 nM and 483 nM, respectively. | ||
M3675 | Rotigotine | Dopamine Receptor |
N-0923; (-)-N 0437 | ||
Rotigotine is a potent dopamine receptor agonist with Ki values of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors and dopamine D1 receptor. Rotigotine a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor. | ||
M3785 | Flupenthixol dihydrochloride | Dopamine Receptor |
Flupenthixol 2HCl | ||
Flupenthixol dihydrochloride is a dopamine receptor antagonist which acts as a Neuroleptic agent as well as an antipsychotic. | ||
M3818 | Rotigotine Hydrochloride | Dopamine Receptor |
Rotigotine HCl;N-0923 Hydrochloride | ||
Rotigotine Hydrochloride (N-0923 Hydrochloride) is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Ki of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor. | ||
M1565 | Quetiapine sulfoxide | 5-HT Receptor |
Quetiapine sulfoxide; Quetiapine S-oxide | ||
Quetiapine sulfoxide is a 5-HT receptor agonist with a pEC50 value of 4.77 for human 5-HT1A. Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC50 value of 6.33 for human D2. | ||
M1564 | Quetiapine Sulfone | 5-HT Receptor |
Quetiapine Sulfone is a 5-HT receptor agonist with a pEC50 value of 4.77 for human 5-HT1A. Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC50 value of 6.33 for human D2. | ||
M1454 | Buspirone | 5-HT Receptor |
Buspirone is an orally active 5-HT1A receptor agonist, and a dopamine D2 autoreceptorsant antagonist. | ||
M4458 | Tetrahydroberberine | Dopamine Receptor |
Canadine; THB | ||
Tetrahydroberberine is an isoquinoline alkaloid isolated from corydalis tuber; has micromolar affinity for dopamine D(2) (pK(i) = 6.08) and 5-HT(1A) (pK(i) = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors (5-HT(1B), 5-HT(1D), 5-HT(3), and 5-HT(4); pK(i) < 5.00). | ||
M4887 | Pardoprunox Hydrochloride | 5-HT Receptor |
SLV-308 | ||
Pardoprunox hydrochloride (DU-126891, SME-308) is an effective agonist of partial dopamine action, corresponding to pEC50 value 8.0. It is also a partial agonist inducing [35S]GTPγS binding, corresponding to pEC50 9.2 and serotonin 5-HT1A receptor 6.3. |
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