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Aripiprazole is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM. Aripiprazole (OPC-14597) is a potent and high-affinity dopamine D2 receptor partial agonist. Aripiprazole shows a greater anti-inflammatory effect on TNF-α, IL-13, IL-17α and fractalkine.
| Molecular Weight | 448.39 |
| Formula | C23H27Cl2N3O2 |
| CAS Number | 129722-12-9 |
| Solubility (25°C) | DMSO 90 mg/mL DMF 40 mg/mL |
| Storage | 4°C, protect from light |
[3] Adrian Preda, et al. A safety evaluation of aripiprazole in the treatment of schizophrenia
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Quetiapine Sulfone is a 5-HT receptor agonist with a pEC50 value of 4.77 for human 5-HT1A. Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC50 value of 6.33 for human D2. |
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| Iloperidone
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