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Immunology/Inflammation Immunology/Inflammation

Cat.No.  Name Information
M4614 Orientin Orientin
M9358 ITE ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), which directly binding to AHR with a Ki of 3 nM.
M10093 α-Galactosyl Ceramide α-Galactosyl Ceramide (KRN 7000, alpha-GalCer) is a potent NKT cell stimulator and selective CD1d ligand. α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory.
M1831 Cyclosporine A Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. cyclosporin A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation.
M20413 4-Biphenylacetic acid 4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors.
M25413 Fucoxanthin Fucoxanthin is a carotenoid that occurs naturally in certain algae with anti-obesity, anti-oxidant, anti-diabetic, anticancer and anti-inflammatory activities.
M2221 Pimecrolimus Pimecrolimus is an immunomodulating agent used in the treatment of atopic dermatitis.
M1803 Laquinimod Laquinimod (ABR-215062) is a new orally active immunoregulator effectively inhibits development and relapses of experimental autoimmune encephalomyelitis.
M55021 MK-4830 MK-4830 is a novel, first-in-class human IgG4 monoclonal antibody targeting the myeloid-specific ILT4 (immunoglobulin-like transcript 4) receptor. MK-4830 catalyzes reprogramming of tumour-associated macrophages, relieving myelosuppression and enhancing T cell function.
M54836 Lobenzarit Lobenzarit is an immunomodulator, possesses anti-oxidative.
M54803 ORIC-533 ORIC-533 is a highly potent and selective, orally bioavailable, Best-in-Class small molecule inhibitor of CD73, an enzyme expressed by various cell types, including immune cells and which catalyzes the generation of adenosine from adenosine monophosphate (AMP).
M41959 BK50164 BK50164 is a potent CD73 inhibitor with an IC50 value of 13.089 µM.
M41958 CCT374705 CCT374705 is an orally active BCL6 inhibitor with potent antiproliferative effects in vitro.
M40481 Mycophenolate Sodium Mycophenolate Sodium is a Mycophenolic acid precursor, as well as an inhibitor of T-lymphocyte proliferation and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).
M31365 Efgartigimod Efgartigimod (ARGX-113) is a human IgG1 antibody Fc-derived fragment and an Fc receptor antagonist that can be used in studies related to autoimmune diseases such as myasthenia gravis (MG), primary immune thrombocytopenia (ITP), and others.
M31316 DiaPep277 DiaPep277 is a peptide containing 24 amino acids based on residues 437 to 460 of Heat Shock Protein 60 (HSP60) for studies related to the immune system in type 1 diabetes.
M29608 MRS4620  MRS4620 is a potent CD73 inhibitor, with a Ki of 0.436 nM. MRS4620 can be use for the research of cancer immunoresearch.
M21029 MRE-269(ACT-333679) MRE-269(ACT-333679) is a prostaglandin I2 (IP) receptor agonist with a binding affinity for the human IP receptor that is 130-fold greater than that for other human prostanoid receptor.
M21012 Loxoprofen Sodium Loxoprofen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) in the propionic acid derivatives group
M20970 Adelmidrol Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities.
M20960 Tinoridine hydrochloride Tinoridine hydrochloride is a non-steroidal anti-inflammatory drug with a potent antiperoxidative activity.
M20939 Diclofenac Epolamine Diclofenac Epolamine is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.
M20675 Etofenamate Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.
M20667 Anisodamine Hydrobromide Anisodamine is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).
M20567 Salicylamide Salicylamide is a non-prescription drug with analgesic and antipyretic properties.
M20561 Picolinic acid (PCL 016) PCL016 is a pyridine carboxylate metabolite of tryptophan and acts as an anti-infective and immunomodulator. It acts by binding with the zinc associated with zinc finger proteins to alter their structure and inhibit function.




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