All AbMole products are for research use only, cannot be used for human consumption.
Orientin is a bioactive compound isolated from medicinal plants that effectively inhibits Sortase A activity with an IC50 of 50.44 ± 0.51 µM. It also inhibits APAP-induced oxidative damage and mitochondrial dysfunction in hepatocytes via Nrf2 and JNK/cytochrome c/caspase-3 signaling pathways. It has antioxidant, anti-inflammatory and anti-cancer activities.
Pharmacol Rep. 2020 Jan 24.
Inhibitory effects of orientin in mast cell-mediated allergic inflammation.
Orientin purchased from AbMole
| Molecular Weight | 448.38 |
| Formula | C21H20O11 |
| CAS Number | 28608-75-5 |
| Solubility (25°C) | 10 mM in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[5] Kit Ying Lam, et al. A Review on Medicinal Properties of Orientin
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