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Orientin

Cat. No. M4614

All AbMole products are for research use only, cannot be used for human consumption.

Orientin Structure
Size Price Availability Quantity
5mg USD 20  USD20 In stock
10mg USD 30  USD30 In stock
20mg USD 50  USD50 In stock
50mg USD 80  USD80 In stock
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Quality Control & Documentation
Biological Activity

Orientin is a bioactive compound isolated from medicinal plants that effectively inhibits Sortase A activity with an IC50 of 50.44 ± 0.51 µM. It also inhibits APAP-induced oxidative damage and mitochondrial dysfunction in hepatocytes via Nrf2 and JNK/cytochrome c/caspase-3 signaling pathways. It has antioxidant, anti-inflammatory and anti-cancer activities.

Product Citations
Chemical Information
Molecular Weight 448.38
Formula C21H20O11
CAS Number 28608-75-5
Solubility (25°C) 10 mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Li Wang, et al. Orientin mediates protection against MRSA-induced pneumonia by inhibiting Sortase A

[2] Cong Qiu, et al. Orientin and vitexin production by a one-pot enzymatic cascade of a glycosyltransferase and sucrose synthase

[3] Zi-Li Kong, et al. Orientin Protects Podocytes from High Glucose Induced Apoptosis through Mitophagy

[4] Chunmeng Li, et al. Orientin suppresses oxidized low-density lipoproteins induced inflammation and oxidative stress of macrophages in atherosclerosis

[5] Kit Ying Lam, et al. A Review on Medicinal Properties of Orientin

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Keywords: Orientin supplier, Immunology/Inflammation, inhibitors, activators

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