Pharmacol Rep. 2020 Jan 24.
Inhibitory effects of orientin in mast cell-mediated allergic inflammation.
Orientin purchased from AbMole
|Solubility (25°C)||10 mM in DMSO|
Powder -20°C 3 years ; 4°C 2 years
In solvent -80°C 6 months ; -20°C 1 month
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
 Li Wang, et al. Orientin mediates protection against MRSA-induced pneumonia by inhibiting Sortase A
 Cong Qiu, et al. Orientin and vitexin production by a one-pot enzymatic cascade of a glycosyltransferase and sucrose synthase
 Zi-Li Kong, et al. Orientin Protects Podocytes from High Glucose Induced Apoptosis through Mitophagy
 Chunmeng Li, et al. Orientin suppresses oxidized low-density lipoproteins induced inflammation and oxidative stress of macrophages in atherosclerosis
 Kit Ying Lam, et al. A Review on Medicinal Properties of Orientin
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