| Cat.No. | Name | Information |
|---|---|---|
| M55368 | 2-Hydroxy Fluorene | 2-Hydroxy Fluorene (2-FLU) has a wide range of applications in life science related research. 2-FLU can increase the expression of psoriasis-related inflammatory factors in HaCaT cells. |
| M55040 | Litifilimab | Litifilimab is a humanized IgG1-κ antibody targeting to C-type lectin domain family 4 member C (CLEC4C). |
| M25413 | Fucoxanthin | Fucoxanthin is a carotenoid that occurs naturally in certain algae with anti-obesity, anti-oxidant, anti-diabetic, anticancer and anti-inflammatory activities. |
| M20413 | 4-Biphenylacetic acid | 4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors. |
| M10093 | α-Galactosyl Ceramide | α-Galactosyl Ceramide (KRN 7000, alpha-GalCer) is a potent NKT cell stimulator and selective CD1d ligand. α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. |
| M9358 | ITE | ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), which directly binding to AHR with a Ki of 3 nM. |
| M4614 | Orientin | Orientin |
| M1831 | Cyclosporine A | Cyclosporine A (CsA，Cyclosporin A) is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. Cyclosporine A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation. |
| M59032 | SMS121 | SMS121 is a novel CD36 inhibitor. SMS121 reduced the uptake of fatty acid into AML cells that could be reversed by addition of free fatty acids and caused decreased cell viability. |
| M58370 | Gemtuzumab | Gemtuzumab is a monoclonal IgG4-κ antibody targeting CD33 antigen, which present on leukemic myeloblasts of acute myeloid leukemia (AML). Gemtuzumab can be used for the synthesis of antibody-drug conjugate (ADC) Gemtuzumab ozogamicin. |
| M55545 | Cyclosporin A-d4 | Cyclosporin A-d4 |
| M55437 | Mycophenolic acid-13c,d3 | Mycophenolic acid-13c,d3 |
| M55358 | Qingdainone | Qingdainone is a natural product that can be obtained from Qingdai. Qingdainone has the potential to study cancer and inflammation |
| M55317 | IA9 TFA | IA9 TFA is a TREM-2 inhibitor. IA9 TFA and can diminish release of proinflammatory cytokines and dramatically suppressed joint inflammation and damage in collagen-Induced Arthritis (CIA) mice model. |
| M55206 | Lintuzumab | Lintuzumab is a humanized monoclonal antibody directed against CD33, which is expressed on the majority of myeloblasts in acute myeloid leukemia. |
| M54780 | Naringenin | Naringenin is the predominant flavanone in Citrus reticulata Blanco, it displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity. |
| M44564 | Tembetarine | Tembetarine exhibits anti-inflammatory and anti-injury properties and acts as an antifeedant against S. frugiperda. |
| M24757 | Denintuzumab | Denintuzumab (hBU 12) is a recombinant humanized anti-CD19 monoclonal antibody. Denintuzumab can be used as the antibody moiety (ADC antibody) of antibody-drug conjugates to synthesize ADC, Denintuzumab Mafodotin (SGN-CD19A). Denintuzumab Mafodotin can be used in the research of acute lymphoblastic leukemia. |
| M21680 | TJ-M2010-5 | TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain of MyD88 to interfere with its homodimerization, and the TLR/MyD88 signal pathway. |
| M21029 | MRE-269 | MRE-269 (ACT-333679) is a prostaglandin I2 (IP) receptor agonist with a binding affinity for the human IP receptor that is 130-fold greater than that for other human prostanoid receptor. |
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