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Immunology/Inflammation Immunology/Inflammation

Cat.No.  Name Information
M25413 Fucoxanthin Fucoxanthin is a carotenoid that occurs naturally in certain algae with anti-obesity, anti-oxidant, anti-diabetic, anticancer and anti-inflammatory activities.
M20413 4-Biphenylacetic acid 4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors.
M10093 α-Galactosyl Ceramide α-Galactosyl Ceramide (KRN 7000, alpha-GalCer) is a potent NKT cell stimulator and selective CD1d ligand. α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory.
M9358 ITE ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), which directly binding to AHR with a Ki of 3 nM.
M4614 Orientin Orientin
M1831 Cyclosporine A Cyclosporine A (CsA,Cyclosporin A) is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. Cyclosporine A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation.
M55545 Cyclosporin A-d4 Cyclosporin A-d4
M55437 Mycophenolic acid-13c,d3 Mycophenolic acid-13c,d3
M55368 2-Hydroxy Fluorene 2-Hydroxy Fluorene (2-FLU) has a wide range of applications in life science related research. 2-FLU can increase the expression of psoriasis-related inflammatory factors in HaCaT cells.
M55358 Qingdainone Qingdainone is a natural product that can be obtained from Qingdai. Qingdainone has the potential to study cancer and inflammation
M55317 IA9 TFA IA9 TFA is a TREM-2 inhibitor. IA9 TFA and can diminish release of proinflammatory cytokines and dramatically suppressed joint inflammation and damage in collagen-Induced Arthritis (CIA) mice model.
M55206 Lintuzumab Lintuzumab is a humanized monoclonal antibody directed against CD33, which is expressed on the majority of myeloblasts in acute myeloid leukemia.
M55047 Evorpacept Evorpacept (ALX148) is a high affinity CD47-blocking fusion protein with an inactive human immunoglobulin Fc region designed to enhance the activity of other anti-neoplastic therapies, with minimal additional toxicity.
M54780 Naringenin Naringenin is the predominant flavanone in Citrus reticulata Blanco, it displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity.
M44564 Tembetarine Tembetarine exhibits anti-inflammatory and anti-injury properties and acts as an antifeedant against S. frugiperda.
M21680 TJ-M2010-5 TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain of MyD88 to interfere with its homodimerization, and the TLR/MyD88 signal pathway.
M20958 Talniflumate Talniflumate is an anti-inflammatory molecule studied and used as a mucin regulator in the treatment of cystic fibrosis, chronic obstructive pulmonary disease (COPD) and asthma.
M20433 Tolmetin Tolmetin is a nonsteroidal anti-inflammatory drug of the heterocyclic acetic acid derivative class and also exhibits analgesic and antipyretic activity.
M20432 5-Acetylsalicylic acid 5-Acetylsalicylic acid is an aminosalicylate anti-inflammatory agent, which has anti-inflammatory and is considered to be the active agent in inflammatory bowel disease (IBD).
M20412 NLRP3 Inflammasome Inhibitor I NLRP3 Inflammasome Inhibitor I, an intermediate substrate in the synthesis of glyburide which is free of the cyclohexylurea moiety involved in insulin release, is a novel inhibitor of the NLRP3 inflammasome.




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