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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M10093 | α-Galactosyl Ceramide | α-Galactosyl Ceramide is a potent NKT cell stimulator and selective CD1d ligand. |
| M9509 | NS-3-008 hydrochloride | NS-3-008 hydrochloride is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2) with an IC50 of 2.25 μM. |
| M9358 | ITE | ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), which directly binding to AHR with a Ki of 3 nM. |
| M9298 | AX-024 hydrochloride | AX-024 hydrochloride is a potent cytokine release inhibitor, inhibits the production of interferon-γ (IFN-γ), interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), IL-10 and IL-17A. |
| M9122 | Tormentic Acid | Tormentic Acid is a natural anti-inflammatory agent which inhibits production of tumor necrosis factor‑α (TNF‑α), interleukin 6 (IL‑6), and IL‑1β. |
| M9117 | W-54011 | W-54011 is a potent, specific, and orally active CD88 (C5a receptor) antagonist, which inhibits the binding of 125I-labeled C5a to human neutrophils with a Ki value of 2.2 nM. |
| M6223 | Tocilizumab | Tocilizumab is a humanized monoclonal antibody that binds to the interleukin-6 receptor, MW: 148 KD. |
| M6219 | Rituximab | Rituximab is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM, MW: 143.86 KD. |
| M4877 | Karminomitsin | Karminomitsin is a very toxic anthracycline-type antineoplastic related to DAUNORUBICIN, obtained from Actinomadura carminata. |
| M4825 | SKQ1 | SKQ1 is a potent mitochondria-targeted antioxidant. |
| M4791 | Tussilagone | Tussilagone is a major active component in Tussilago farfara, has anti-inflammatory effect. |
| M4790 | β-demonic-acid | β-demonic-acid exhibits anti-inflammatory effects. |
| M4750 | Echinocystic-acid | Echinocystic-acid |
| M4724 | Leonurine hydrochloride | Leonurine hydrochloride |
| M4704 | Diosgenin-glucoside | Diosgenin-glucoside is a saponin compound extracted from Tritulus terrestris L., protects against spinal cord injury by regulating autophagy and alleviating apoptosis. |
| M4686 | Eriodictyol | Eriodictyol |
| M4614 | Orientin | Orientin |
| M4389 | Carnosol | Carnosol is a phenolic diterpene with antioxidant and anticarcinogenic activities. |
| M4139 | Salvianolic-acid-A | Salvianolic-acid-A |
| M3998 | Rhein | Rhein, also known as cassic acid, is a substance in the anthraquinone group obtained from rhubarb. |
| M3634 | TAPI-1 | TAPI-1 is an ADAM17/TACE inhibitor that blocks shedding of cytokine receptors with IC50 value of 8.09 microM. |
| M3468 | Methylprednisolone | Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. |
| M3416 | Mycophenolic acid | Mycophenolic acid is an immunosuppressant agent used to prevent rejection in organ transplantation. |
| M3297 | Meloxicam | Meloxicam (Mobic) is a nonsteroidal anti-inflammatory agent with analgesic and fever reducer effects. |
| M2221 | Pimecrolimus | Pimecrolimus is an immunomodulating agent used in the treatment of atopic dermatitis. |
| M2098 | Bindarit | Bindarit is a specific anti-inflammatory small molecule inhibitor of MCP-1 production. |
| M1831 | Cyclosporine A | Cyclosporine A is a powerful immunosuppressive agent that inhibits the T-cell receptor signal transduction pathway. |
| M1803 | Laquinimod | Laquinimod (ABR-215062) is a new orally active immunoregulator effectively inhibits development and relapses of experimental autoimmune encephalomyelitis. |
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