| Cat.No. | Name | Information |
|---|---|---|
| M4614 | Orientin | Orientin |
| M9358 | ITE | ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), which directly binding to AHR with a Ki of 3 nM. |
| M10093 | α-Galactosyl Ceramide | α-Galactosyl Ceramide (KRN 7000, alpha-GalCer) is a potent NKT cell stimulator and selective CD1d ligand. α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. |
| M1831 | Cyclosporine A | Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. cyclosporin A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation. |
| M20413 | 4-Biphenylacetic acid | 4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors. |
| M25413 | Fucoxanthin | Fucoxanthin is a carotenoid that occurs naturally in certain algae with anti-obesity, anti-oxidant, anti-diabetic, anticancer and anti-inflammatory activities. |
| M9730 | B7/CD28 interaction inhibitor 1 | CTLA-4 inhibitor 1 is a potent B7.1-CD28 interaction inhibitor with IC50 of 50 nM. |
| M9509 | NS-3-008 hydrochloride | NS-3-008 hydrochloride is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2) with an IC50 of 2.25 μM. |
| M9298 | AX-024 hydrochloride | Ax-024 Hydrochloride is orally available, the first tCR-NCK interaction inhibitor that selectively inhibits TCR-induced T cell activation with an IC50 value of 1 nM. Ax-024 Hydrochloride regulates cellular signaling by targeting the SH3 domain. Ax-024 Hydrochloride has the characteristics of low toxicity, high efficiency and high selectivity. |
| M9122 | Tormentic Acid | Tormentic Acid is a natural anti-inflammatory agent which inhibits production of tumor necrosis factor‑α (TNF‑α), interleukin 6 (IL‑6), and IL‑1β. |
| M9117 | W-54011 | W-54011 is a potent, specific, and orally active CD88 (C5a receptor) antagonist, which inhibits the binding of 125I-labeled C5a to human neutrophils with a Ki value of 2.2 nM. |
| M9052 | ST2825 | ST-2825 is MyD88 inhibitor. |
| M5707 | Indoprofen | Indoprofen is a non-steroidal anti-inflammatory compound, provide insight into treatments for spinal muscular atrophies. |
| M4877 | Karminomitsin | Karminomitsin is a very toxic anthracycline-type antineoplastic related to DAUNORUBICIN, obtained from Actinomadura carminata. |
| M4825 | SKQ1 | SKQ1 is a potent mitochondria-targeted antioxidant. |
| M4791 | Tussilagone | Tussilagone is a major active component in Tussilago farfara, has anti-inflammatory effect. |
| M4790 | β-demonic-acid | β-demonic-acid exhibits anti-inflammatory effects. |
| M4750 | Echinocystic-acid | Echinocystic-acid |
| M4724 | Leonurine hydrochloride | Leonurine hydrochloride is an alkaloid isolated from Herba leonuri, with anti-oxidative and anti-inflammatory. |
| M4686 | Eriodictyol | Eriodictyol is a flavonoid obtained from Chinese herbs, which has antioxidant and anti-inflammatory properties. Eriodictyol can induce Nrf2 signaling pathway. Eriodictyol is also an influenza dependent RNA polymerase inhibitor with an IC50 of 18 nM. |
| M4389 | Carnosol | Carnosol is a phenolic diterpene with antioxidant and anticarcinogenic activities. |
| M4139 | Salvianolic-acid-A | Salvianolic-acid-A |
| M3634 | TAPI-1 | TAPI-1 is an ADAM17/TACE inhibitor that blocks shedding of cytokine receptors with IC50 value of 8.09 microM. |
| M3468 | Methylprednisolone | Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. |
| M3416 | Mycophenolic acid | Mycophenolic acid is an immunosuppressant agent used to prevent rejection in organ transplantation. |
| M3297 | Meloxicam | Meloxicam (Mobic) is a nonsteroidal anti-inflammatory agent with analgesic and fever reducer effects. |
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