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Fucoxanthin

Cat. No. M25413
Fucoxanthin Structure
Synonym:

all-trans-Fucoxanthin

Size Price Availability Quantity
10mg USD 150  USD150 In stock
25mg USD 345  USD345 In stock
50mg USD 630  USD630 In stock
100mg USD 1125  USD1125 In stock
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Quality Control & Documentation
Biological Activity

Fucoxanthin is a carotenoid that occurs naturally in certain algae with anti-obesity, anti-oxidant, anti-diabetic, anticancer and anti-inflammatory activities.

Product Citations
Chemical Information
Molecular Weight 658.91
Formula C42H58O6
CAS Number 3351-86-8
Solubility (25°C) DMSO 12 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Yam Sim Khaw, et al. Mar Drugs. Fucoxanthin Production of Microalgae under Different Culture Factors: A Systematic Review

[2] Hu Mao, et al. Oxid Med Cell Longev. Fucoxanthin Attenuates Oxidative Damage by Activating the Sirt1/Nrf2/HO-1 Signaling Pathway to Protect the Kidney from Ischemia-Reperfusion Injury

[3] Liao Zhiyin, et al. Biomed Pharmacother. Fucoxanthin rescues dexamethasone induced C2C12 myotubes atrophy

[4] Mingjun Liu, et al. Life Sci. Fucoxanthin: A promising compound for human inflammation-related diseases

[5] Maria Alessandra Gammone, et al. Mar Drugs. Anti-obesity activity of the marine carotenoid fucoxanthin

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