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Immunology/Inflammation Immunology/Inflammation

Cat.No.  Name Information
M4614 Orientin Orientin
M9358 ITE ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR), which directly binding to AHR with a Ki of 3 nM.
M10093 α-Galactosyl Ceramide α-Galactosyl Ceramide (KRN 7000, alpha-GalCer) is a potent NKT cell stimulator and selective CD1d ligand. α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory.
M1831 Cyclosporine A Cyclosporin A is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. cyclosporin A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation.
M20413 4-Biphenylacetic acid 4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors.
M25413 Fucoxanthin Fucoxanthin is a carotenoid that occurs naturally in certain algae with anti-obesity, anti-oxidant, anti-diabetic, anticancer and anti-inflammatory activities.
M41958 CCT374705 CCT374705 is an orally active BCL6 inhibitor with potent antiproliferative effects in vitro.
M40481 Mycophenolate Sodium Mycophenolate Sodium is a Mycophenolic acid precursor, as well as an inhibitor of T-lymphocyte proliferation and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).
M31365 Efgartigimod Efgartigimod (ARGX-113) is a human IgG1 antibody Fc-derived fragment and an Fc receptor antagonist that can be used in studies related to autoimmune diseases such as myasthenia gravis (MG), primary immune thrombocytopenia (ITP), and others.
M31316 DiaPep277 DiaPep277 is a peptide containing 24 amino acids based on residues 437 to 460 of Heat Shock Protein 60 (HSP60) for studies related to the immune system in type 1 diabetes.
M29608 MRS4620  MRS4620 is a potent CD73 inhibitor, with a Ki of 0.436 nM. MRS4620 can be use for the research of cancer immunoresearch.
M21029 MRE-269(ACT-333679) MRE-269(ACT-333679) is a prostaglandin I2 (IP) receptor agonist with a binding affinity for the human IP receptor that is 130-fold greater than that for other human prostanoid receptor.
M21012 Loxoprofen Sodium Loxoprofen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) in the propionic acid derivatives group
M20970 Adelmidrol Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities.
M20960 Tinoridine hydrochloride Tinoridine hydrochloride is a non-steroidal anti-inflammatory drug with a potent antiperoxidative activity.
M20939 Diclofenac Epolamine Diclofenac Epolamine is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.
M20675 Etofenamate Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.
M20667 Anisodamine Hydrobromide Anisodamine is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).
M20567 Salicylamide Salicylamide is a non-prescription drug with analgesic and antipyretic properties.
M20561 Picolinic acid (PCL 016) PCL016 is a pyridine carboxylate metabolite of tryptophan and acts as an anti-infective and immunomodulator. It acts by binding with the zinc associated with zinc finger proteins to alter their structure and inhibit function.
M20544 Trans-Tranilast Trans-Tranilast is an antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.
M20536 Setipiprant (ACT-129968, KYTH-105) Setipiprant(ACT-129968, KYTH-105) is a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2) that that has been shown to have greater specificity for DP2 (CRTH2) than for DP1.
M20448 Actarit Actarit is an orally active immunomodulator used in the treatment of rheumatoid arthritis.
M20418 Dehydroandrographolide Succinate Potasium Salt Dehydroandrographolide Succinate (DAS), extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect.
M18777 Protostemonine Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo. Protostemonine shows significant antitussive activity in a citric acid-induced guinea pig cough model following peripheral administration.




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