All AbMole products are for research use only, cannot be used for human consumption.
B7/CD28 interaction inhibitor 1 is a potent B7.1-CD28 interaction inhibitor with IC50 of 50 nM. Blocking B7/CD28 interactions with monoclonal antibodies or soluble receptors results in immunosuppression and enhanced allograft survival, while B7/CTLA-4 blockade results in enhanced antitumor immune responses. The interaction of co-stimulatory molecules on T cells with B7 molecules on antigen presenting cells plays an important role in the activation of naive T cells.
| Molecular Weight | 427.35 |
| Formula | C21H13F4N5O |
| CAS Number | 635324-72-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Immunology/Inflammation Products |
|---|
| Qingdainone
Qingdainone is a natural product that can be obtained from Qingdai. Qingdainone has the potential to study cancer and inflammation |
| IA9 TFA
IA9 TFA is a TREM-2 inhibitor. IA9 TFA and can diminish release of proinflammatory cytokines and dramatically suppressed joint inflammation and damage in collagen-Induced Arthritis (CIA) mice model. |
| Thymosin alpha 1
Thymosin alpha 1 (Tα1), a 28-amino acid peptide, is a peptide naturally occurring in the thymus that has long been recognized for modifying, enhancing, and restoring immune function. Thymosin alpha 1 (Tα1) can enhance T-cell, dendritic cell (DC) and antibody responses, modulate cytokines and chemokines production and block steroid-induced apoptosis of thymocytes. |
| Lintuzumab
Lintuzumab is a humanized monoclonal antibody directed against CD33, which is expressed on the majority of myeloblasts in acute myeloid leukemia. |
| Evorpacept
Evorpacept (ALX148) is a high affinity CD47-blocking fusion protein with an inactive human immunoglobulin Fc region designed to enhance the activity of other anti-neoplastic therapies, with minimal additional toxicity. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
