| Cat.No. | Name | Information |
|---|---|---|
| M1969 | Doxorubicin HCL | Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. |
| M2082 | Stzocin | Streptozotocin (Streptozocin; STZ; Stzocin) is an antibiotic widely used in experimental animal models of induced diabetes. Streptozotocin enters B cells via the glucose transporter (GLUT2) and causes the alkylation of DNA ( DNA-methylating ). Streptozotocin can induce the apoptosis of β cells. *The compound is unstable in solutions, freshly prepared is recommended |
| M2227 | Imiquimod | Imiquimod (R837), an imidazoquinoline amine analog to guanosine, is a selective toll like receptor 7 (TLR7) agonist. with potent indirect antiviral activity. |
| M5152 | Sodium Butyrate | Sodium butyrate is the sodium salt of butyric acid, which has been reported to cause hyperacetylation of histones due to its role as a HDAC inhibitor with IC50 values of 0.3, 0.4, 0.3 mM for HDAC1, 2 and 7 respectively. Can be used to construct animal models of venous stenosis. |
| M3637 | Puromycin dihydrochloride | Puromycin dihydrochloride is an aminonucleoside antibiotic that acts as a protein synthesis inhibitor. |
| M3699 | Letrozole | Letrozole is an orally active, potent, selective, nonsteroidal, third-generation aromatase (CYP19A1) inhibitor, a synthetic benzyltriazole derivative, which is used in the construction of animal models of polycystic ovary syndrome (PCOS), as well as in studies related to postoperative hormone-responsive breast cancer. |
| M5688 | Heparin sodium | Heparin sodium salt, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. |
| M9524 | Lipopolysaccharides | Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. This product is derived from Escherichia coli O55:B5. |
| M6209 | Rattan root extract | Rotenone is a mitochondrial electron transport chain complex I inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. |
| M3671 | Cyc-pham monohydrate | Cyclophosphamide monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA. *The compound is unstable in solutions, freshly prepared is recommended |
| M25525 | Thyroglobulin (from bovine thyroid) | Thyroglobulin is an excellent source of N-linked glycans of various structures, including sialylated core fucose and oligomannose oligosaccharides. Native thyroglobulin, consisting of two polypeptide homodimers of 330 kDa each, purified from bovine thyroid. |
| M25524 | Freund′s Adjuvant, Complete | AbMole Freund′s Adjuvant, Complete is formulated with low endotoxin, high-purity paraffin oil and mannide monooleate and Mycobacterium tuberculosis (heat killed and dried), without preservatives. It is one of the most commonly used immune adjuvants in the preparation of antibodies for animal immunization. |
| M25463 | 4-Vinylcyclohexene diepoxide | 4-Vinylcyclohexene diepoxide (VCD) is an ovine toxin which may be used to study and understand its effect on ovarian follicles and effects on epithelial differentiation. |
| M21865 | Biuret | Biuret |
| M21633 | Keyhole limpet hemocyanin | Keyhole limpet hemocyanin is a copper protein that binds reversibly to oxygen, and it is lime green when oxidized and white when reduced. Keyhole limpet hemocyanin has oxygen-carrying function, antiviral activity, antibacterial activity, and coagulation function. |
| M21581 | Magnesium sulfate | Magnesium sulfate is an inorganic salt that acts as a calcium channel blocker and also has anticonvulsant activity. It can be used to construct animal models of functional diarrhea. |
| M21537 | Urokinase | Urokinase is a proteolytic enzyme. It has potent antithrombotic activity and has a local vasodilatory effect. It can be used to construct animal models of deep vein thrombosis. |
| M21433 | Pentetrazol (98%) | Pentetrazol (PTZ), a tetrazole derivative, is an inhibitor of gamma aminobutyric acid (GABAA) and its receptor complex. PTZ is a convulsive agent used to induce convulsions. It can penetrate the blood-brain barrier. |
| M19987 | 2-Iodoacetamide | 2-Iodoacetamide is an alkylating agent that is commonly used to alkylate cysteines during proteomic sample preparation.It can be used to construct animal models of functional dyspepsia. |
| M18437 | Taurocholic acid sodium | Taurocholic acid sodium (Sodium taurocholate) is a bile salt that can be used to construct models of acute pancreatitis in rats. Taurocholic acid sodium has immunoregulation effect. |
| M14800 | L-Thyroxine sodium | L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4). |
| M11554 | Pristane | Pristane (Norphytane) is a naturally saturated terpene alkane found in small amounts in many plants, various Marine organisms, and is the most active component in mineral oils. Pristane is a non-antigenic adjuvant that induces MHC Class II restrictive arthritis T cells in rats. |
| M11540 | Propranolol | Propranolol is a non-selective β-adrenergic receptor (βAR) antagonist, which has high affinity for β1AR and β2AR with Ki value of 1.8 nM and 0.8 nM, respectively. Propranolol inhibited the binding of [3H]-DHA to rat meninges with an IC50 of 12 nM. It can be used to construct animal models of psoriasis. |
| M11502 | Hydroquinone | Hydroquinone is an inhibitor and antioxidant used as a synthetic intermediate in dyes, engine fuels, and oils. It also has antioxidant properties and produces toxic effects in multiple organs, especially the kidneys. It can be used to construct animal models of vitiligo. |
| M11477 | Colcemid | Colcemid (Demecolcine) is an effective mitotic inhibitor. Colcemid binds tubulin and blocks cells for metaphase karyotype analysis. Colcemid can induce apoptosis and can be used in tumor research. |
| M10341 | Lauric acid | Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. |
| M10276 | Elastase (from porcine pancreas) | Elastase from porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide. |
| M10195 | MOG (35-55) (Mouse, rat) | MOG (35-55) (Mouse, rat) is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat has encephalitogenic activity and induces T cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat induces Th1 cytokine response as well as relatively high levels of IgG antibodies. |
| M9977 | Lithium chloride | Lithium chloride can be used to induce epilepsy model. |
| M9976 | D-Galactose | D-Galactose is a natural aldohexose and C-4 epimer of glucose, it accelerates the aging of invertebrates and mammals and is used as a model of aging. |
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