| Cat.No. | Name | Information |
|---|---|---|
| M1969 | Doxorubicin HCL | Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. |
| M2082 | Streptozotocin | Streptozotocin (STZ) is a kind of glucosamine - nitrosourea derivative. *The compound is unstable in solutions, freshly prepared is recommended |
| M2227 | Imiquimod | Imiquimod (R837), an imidazoquinoline amine analog to guanosine, is a selective toll like receptor 7 (TLR7) agonist. with potent indirect antiviral activity. |
| M5152 | Sodium Butyrate | Sodium butyrate is the sodium salt of butyric acid, which has been reported to cause hyperacetylation of histones due to its role as a HDAC inhibitor with IC50 values of 0.3, 0.4, 0.3 mM for HDAC1, 2 and 7 respectively. Can be used to construct animal models of venous stenosis. |
| M3637 | Puromycin dihydrochloride | Puromycin dihydrochloride is an aminonucleoside antibiotic that acts as a protein synthesis inhibitor. |
| M3699 | Letrozole | Letrozole is an orally active, potent, selective, nonsteroidal, third-generation aromatase (CYP19A1) inhibitor, a synthetic benzyltriazole derivative, which is used in the construction of animal models of polycystic ovary syndrome (PCOS), as well as in studies related to postoperative hormone-responsive breast cancer. |
| M5688 | Heparin sodium | Heparin sodium salt, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. |
| M9524 | Lipopolysaccharides | Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. This product is derived from Escherichia coli O55:B5. |
| M6209 | Rotenone | Rotenone is an inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase, and is used to induce a Parkinson-like syndrome as an experimental model in rats. |
| M3671 | Cyclophosphamide monohydrate | Cyclophosphamide monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA. *The compound is unstable in solutions, freshly prepared is recommended |
| M14800 | L-Thyroxine sodium | L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4). |
| M13641 | Bleomycin hydrochloride | Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic. |
| M13340 | Uric acid | Uric acid is a scavenger of oxygen radical, a very important antioxidant and a product of the metabolic decomposition of purine nucleotides. Helps maintain stable blood pressure and fights oxidative stress. Uric acid removes reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite and inhibits lipid peroxidation. It can be used to induce animal models of uric acid nephropathy. |
| M11554 | Pristane | Pristane (Norphytane) is a naturally saturated terpene alkane found in small amounts in many plants, various Marine organisms, and is the most active component in mineral oils. Pristane is a non-antigenic adjuvant that induces MHC Class II restrictive arthritis T cells in rats. |
| M11540 | Propranolol | Propranolol is a non-selective β-adrenergic receptor (βAR) antagonist, which has high affinity for β1AR and β2AR with Ki value of 1.8 nM and 0.8 nM, respectively. Propranolol inhibited the binding of [3H]-DHA to rat meninges with an IC50 of 12 nM. It can be used to construct animal models of psoriasis. |
| M11477 | Colcemid | Colcemid (Demecolcine) is an effective mitotic inhibitor. Colcemid binds tubulin and blocks cells for metaphase karyotype analysis. Colcemid can induce apoptosis and can be used in tumor research. |
| M11029 | Thioacetamide | Thioacetamide (TAA), a hepatotoxin commonly used for experimental purposes, causes necrosis in the center of the lobule after a single administration and can be used to construct animal models of liver injury. |
| M10552 | β-Aminopropionitrile (Liquid) | β-Aminopropionitrile is a specific and irreversible lysyl oxidase (LOX) inhibitor. |
| M10449 | Oleic acid (Liquid) | Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid. Oleic acid is also a Na+/K+ ATPase activator. |
| M10355 | Uric acid sodium | Uric acid sodium is a scavenger of oxygen radical, it is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. |
| M10341 | Lauric acid | Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. |
| M10276 | Elastase (from porcine pancreas) | Elastase from porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide. |
| M10195 | MOG (35-55) (Mouse, rat) | MOG (35-55) (Mouse, rat) is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat has encephalitogenic activity and induces T cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat induces Th1 cytokine response as well as relatively high levels of IgG antibodies. |
| M10041 | MPP+ iodide | MPP+ iodide is a toxic metabolite of the neurotoxin MPTP, MPP+ iodide causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. |
| M9977 | Lithium chloride | Lithium chloride can be used to induce epilepsy model. |
| M9976 | D-Galactose | D-Galactose is a natural aldohexose and C-4 epimer of glucose, it accelerates the aging of invertebrates and mammals and is used as a model of aging. |
| M9975 | 7,12-Dimethylbenz[a]anthracene | 7,12-Dimethylbenz[a]anthracene is a polycyclic aromatic hydrocarbon. |
| M9974 | L-Methionine | L-Methionine is an essential amino acid for metabolism. |
| M9972 | Alloxan monohydrate | Alloxan monohydrate is a kind of hydrated alloxan, it can be used to induce diabetes model research. |
| M9941 | Hyaluronidase (from sheep testes) | Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds. In addition, Hyaluronidase can be used to construct animal models of retinal detachment. |
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