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Animal Modeling

Cat.No.  Name Information
M1969 Doxorubicin HCL Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
M2082 Streptozotocin Streptozotocin (STZ) is a kind of glucosamine - nitrosourea derivative. *The compound is unstable in solutions, freshly prepared is recommended
M2227 Imiquimod Imiquimod (R837), an imidazoquinoline amine analog to guanosine, is a selective toll like receptor 7 (TLR7) agonist. with potent indirect antiviral activity.
M5152 Sodium Butyrate Sodium butyrate is the sodium salt of butyric acid, which has been reported to cause hyperacetylation of histones due to its role as a HDAC inhibitor with IC50 values of 0.3, 0.4, 0.3 mM for HDAC1, 2 and 7 respectively. Can be used to construct animal models of venous stenosis.
M3637 Puromycin dihydrochloride Puromycin dihydrochloride is an aminonucleoside antibiotic that acts as a protein synthesis inhibitor.
M3699 Letrozole Letrozole is an orally active, potent, selective, nonsteroidal, third-generation aromatase (CYP19A1) inhibitor, a synthetic benzyltriazole derivative, which is used in the construction of animal models of polycystic ovary syndrome (PCOS), as well as in studies related to postoperative hormone-responsive breast cancer.
M5688 Heparin sodium Heparin sodium salt, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule.
M9524 Lipopolysaccharides Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. This product is derived from Escherichia coli O55:B5.
M6209 Rotenone Rotenone is an inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase, and is used to induce a Parkinson-like syndrome as an experimental model in rats.
M3671 Cyclophosphamide monohydrate Cyclophosphamide monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA. *The compound is unstable in solutions, freshly prepared is recommended
M25525 Thyroglobulin (from bovine thyroid) Thyroglobulin is an excellent source of N-linked glycans of various structures, including sialylated core fucose and oligomannose oligosaccharides. Native thyroglobulin, consisting of two polypeptide homodimers of 330 kDa each, purified from bovine thyroid.
M25524 Freund′s Adjuvant, Complete AbMole Freund′s Adjuvant, Complete is formulated with low endotoxin, high-purity paraffin oil and mannide monooleate and Mycobacterium tuberculosis (heat killed and dried), without preservatives. It is one of the most commonly used immune adjuvants in the preparation of antibodies for animal immunization.
M25463 4-Vinylcyclohexene diepoxide 4-Vinylcyclohexene diepoxide (VCD) is an ovine toxin which may be used to study and understand its effect on ovarian follicles and effects on epithelial differentiation.
M21865 Biuret Biuret
M21633 Keyhole limpet hemocyanin Keyhole limpet hemocyanin is a copper protein that binds reversibly to oxygen, and it is lime green when oxidized and white when reduced. Keyhole limpet hemocyanin has oxygen-carrying function, antiviral activity, antibacterial activity, and coagulation function.
M21581 Magnesium sulfate Magnesium sulfate is an inorganic salt that acts as a calcium channel blocker and also has anticonvulsant activity. It can be used to construct animal models of functional diarrhea.
M21537 Urokinase Urokinase is a proteolytic enzyme. It has potent antithrombotic activity and has a local vasodilatory effect. It can be used to construct animal models of deep vein thrombosis.
M21433 Pentetrazol (98%) Pentetrazol (PTZ), a tetrazole derivative, is an inhibitor of gamma aminobutyric acid (GABAA) and its receptor complex. PTZ is a convulsive agent used to induce convulsions. It can penetrate the blood-brain barrier.
M20931 Benzalkonium chloride Benzalkonium chloride is a cationic surface-acting agent containing the quaternary ammonium group
M19987 2-Iodoacetamide 2-Iodoacetamide is an alkylating agent that is commonly used to alkylate cysteines during proteomic sample preparation.It can be used to construct animal models of functional dyspepsia.
M18437 Taurocholic acid sodium Taurocholic acid sodium (Sodium taurocholate) is a bile salt that can be used to construct models of acute pancreatitis in rats. Taurocholic acid sodium has immunoregulation effect.
M17200 Dibutyl phthalate Dibutyl phthalate is a phthalate ester that is also an inhibitor of alpha-glucosidase (alpha-Glu). In addition, Dibutyl phthalate can also be used to construct a rat model of hypospadias.
M14800 L-Thyroxine sodium L-Thyroxine sodium (Levothyroxine sodium) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4).
M13641 Bleomycin hydrochloride Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic.
M11554 Pristane Pristane (Norphytane) is a naturally saturated terpene alkane found in small amounts in many plants, various Marine organisms, and is the most active component in mineral oils. Pristane is a non-antigenic adjuvant that induces MHC Class II restrictive arthritis T cells in rats.
M11540 Propranolol Propranolol is a non-selective β-adrenergic receptor (βAR) antagonist, which has high affinity for β1AR and β2AR with Ki value of 1.8 nM and 0.8 nM, respectively. Propranolol inhibited the binding of [3H]-DHA to rat meninges with an IC50 of 12 nM. It can be used to construct animal models of psoriasis.
M11502 Hydroquinone Hydroquinone is an inhibitor and antioxidant used as a synthetic intermediate in dyes, engine fuels, and oils. It also has antioxidant properties and produces toxic effects in multiple organs, especially the kidneys. It can be used to construct animal models of vitiligo.
M11477 Colcemid Colcemid (Demecolcine) is an effective mitotic inhibitor. Colcemid binds tubulin and blocks cells for metaphase karyotype analysis. Colcemid can induce apoptosis and can be used in tumor research.
M11029 Thioacetamide Thioacetamide (TAA), a hepatotoxin commonly used for experimental purposes, causes necrosis in the center of the lobule after a single administration and can be used to construct animal models of liver injury.
M10449 Oleic acid Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid. Oleic acid is also a Na+/K+ ATPase activator.




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