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Animal Modeling

Cat.No.  Name Information
M1969 Doxorubicin HCL Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
M2082 Stzocin Streptozotocin (Streptozocin; STZ; Stzocin) is an antibiotic widely used in experimental animal models of induced diabetes. Streptozotocin enters B cells via the glucose transporter (GLUT2) and causes the alkylation of DNA ( DNA-methylating ). Streptozotocin can induce the apoptosis of β cells. *The compound is unstable in solutions, freshly prepared is recommended
M2227 Imiquimod Imiquimod (R837), an imidazoquinoline amine analog to guanosine, is a selective toll like receptor 7 (TLR7) agonist. with potent indirect antiviral activity.
M5152 Sodium Butyrate Sodium butyrate is the sodium salt of butyric acid, which has been reported to cause hyperacetylation of histones due to its role as a HDAC inhibitor with IC50 values of 0.3, 0.4, 0.3 mM for HDAC1, 2 and 7 respectively. Can be used to construct animal models of venous stenosis.
M3637 Puromycin dihydrochloride Puromycin dihydrochloride is an aminonucleoside antibiotic that acts as a protein synthesis inhibitor.
M3699 Letrozole Letrozole is an orally active, potent, selective, nonsteroidal, third-generation aromatase (CYP19A1) inhibitor, a synthetic benzyltriazole derivative, which is used in the construction of animal models of polycystic ovary syndrome (PCOS), as well as in studies related to postoperative hormone-responsive breast cancer.
M5688 Heparin sodium Heparin sodium salt, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule.
M9524 Lipopolysaccharides Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. This product is derived from Escherichia coli O55:B5.
M6209 Rattan root extract Rotenone is a mitochondrial electron transport chain complex I inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production.
M3671 Cyc-pham monohydrate Cyclophosphamide monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA. *The compound is unstable in solutions, freshly prepared is recommended
M3891 Calcipotriol Calcipotriol is a 1,25-Dihydroxyvitamin D3 analogue which is used for the research of psoriasis. *The compound is unstable in solutions, freshly prepared is recommended
M3738 Oxonic acid potassium salt Oxonic acid potassium salt is an inhibitor of uricase.
M3521 Fluticasone propionate Fluticasone propionate (Flonase, Veramyst) is a synthetic corticosteroid which is derived from fluticasone used to treat asthma and allergic rhinitis (hay fever).
M3453 Scopolamine hydrobromide Scopolamine HBr is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.It can be used to construct animal models of dry eye.
M3384 Diethylstilbestrol Diethylstilbestrol is a synthetic nonsteroidal estrogen that can be used to construct animal models of primary dysmenorrhea.
M3325 Captopril Captopril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM. It can be used to construct animal models of heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM.
M3232 Cortisone acetate Cortisone acetate is the acetate form of Cortisone, a steroid hormone and glucocorticoid that suppresses the immune system, thereby reducing inflammatory pain and swelling at the site of injury.Cortisone acetate and epinephrine, the primary hormones released by the body in response to stress, elevate blood pressure. They can be used to construct animal models of hypertension.
M3215 Adenine Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry.
M2944 Pilocarpine hydrochloride Pilocarpine hydrochloride is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy. *The compound is unstable in solutions, freshly prepared is recommended
M2683 Estradiol Benzoate Estradiol Benzoate is an estrogen analog and an estrogen receptor (ER) agonist that binds to human, murine, and chicken ERα with an IC50 in the range of 22-28 nM.In addition, Estradiol Benzoate can be used in animal disease models (e.g., rat bacterial vaginitis model, rat prostatitis model, etc.). Construct.
M2626 Dexamethasone Sodium Phosphate Dexamethasone Sodium Phosphate is a glucocorticoid receptor agonist that induces the production of lipocortin, a phospholipase A2 inhibitory protein. Dexamethasone inhibits autophagy levels in damaged cells in a dose-dependent manner. It can be used to construct models of allergic conjunctivitis.
M2625 Dexamethasone acetate Dexamethasone acetate is a potent glucocorticoid-like synthetic that inhibits the pituitary-adrenal axis. It can be used to construct animal models of atopic dermatitis.
M2619 Deoxycorticosterone acetate Deoxycorticosterone acetate, an adrenocorticotropic hormone and also a precursor of aldosterone, as well as a salicorticoid receptor (MR) agonist, can be used to construct rat models of hypertension.
M2548 Cysteamine hydrochloride Cysteamine HCl, the hydrochloride form of Cysteamine, is also a transglutaminase 2 (TGM2) inhibitor, which can be used to induce gastrointestinal disorders in a mouse model as well as a duodenal ulcer model. In addition, Cysteamine HCl has the ability to modulate the activity of dopamine neurons in the striatum of awake, freely moving rats by inhibiting the increased dopamine release from amphetamine, and has antioxidant activity.
M2440 Benzbromarone Benzbromarone is a URAT1 inhibitor that inhibits MDCKII cells over-expressing URAT1 with an IC50 of 0.190 μM.
M2145 Loperamide hydrochloride Loperamide hydrochloride is a high affinity μ-opioid receptor agonist with peripheral selectivity with Ki values of 2, 48 and 1156 nM for μ-, δ- and κ-opioid receptors respectively. Loperamide hydrochloride is also a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. It can be used to construct animal models of functional constipation.
M53993 PLP (139-151) PLP (139-151) is amino acid residue 139 to 151 of myelin proteolipid protein (PLP) used to induce experimental autoimmune encephalomyelitis (EAE).
M50254 G6PI 325-339 (human) G6PI 325-339 (human) is an efficient inducer of arthritis in B10.Q mice.
M50240 Heparin sodium salt (MW 15kDa) Heparin sodium salt (MW 15kDa) is a heparin polymer with a molecular weight of 15kDa.Heparin sodium salt is an anticoagulant that reversibly binds to antithrombin III (ATIII), thereby accelerating the rate of inactivation of Thrombin factor IIa and factor Xa by ATIII. Heparin sodium salt is used for blood collection and plasma preparation in experimental animals and for the construction of parenteral nutrition models in mice.
M49464 1-Butyl-1-nitrosourea 1-Butyl-1-nitrosourea can be used to construct animal models of leukemia.




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