| Cat.No. | Name | Information |
|---|---|---|
| M1969 | Doxorubicin HCL | Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. |
| M2082 | Streptozotocin | Streptozotocin (STZ) is a kind of glucosamine - nitrosourea derivative. *The compound is unstable in solutions, freshly prepared is recommended |
| M2227 | Imiquimod | Imiquimod (R837), an imidazoquinoline amine analog to guanosine, is a selective toll like receptor 7 (TLR7) agonist. with potent indirect antiviral activity. |
| M5152 | Sodium Butyrate | Sodium butyrate is the sodium salt of butyric acid, which has been reported to cause hyperacetylation of histones due to its role as a HDAC inhibitor with IC50 values of 0.3, 0.4, 0.3 mM for HDAC1, 2 and 7 respectively. Can be used to construct animal models of venous stenosis. |
| M3637 | Puromycin dihydrochloride | Puromycin dihydrochloride is an aminonucleoside antibiotic that acts as a protein synthesis inhibitor. |
| M3699 | Letrozole | Letrozole is an orally active, potent, selective, nonsteroidal, third-generation aromatase (CYP19A1) inhibitor, a synthetic benzyltriazole derivative, which is used in the construction of animal models of polycystic ovary syndrome (PCOS), as well as in studies related to postoperative hormone-responsive breast cancer. |
| M5688 | Heparin sodium | Heparin sodium salt, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. |
| M9524 | Lipopolysaccharides | Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. This product is derived from Escherichia coli O55:B5. |
| M6209 | Rotenone | Rotenone is an inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase, and is used to induce a Parkinson-like syndrome as an experimental model in rats. |
| M3671 | Cyclophosphamide monohydrate | Cyclophosphamide monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA. *The compound is unstable in solutions, freshly prepared is recommended |
| M5666 | Furazolidone | Furazolidone is a synthetic nitrofuran derivative with bactericidal or bacteriostatic activity when used against Gram-positive and Gram-negative bacteria. It can be used to construct animal models of cardiomyopathy. |
| M5647 | Finasteride | Finasteride is an orally active, potent and reversible steroid type II 5α-reductase (SRD5A2) inhibitor with an IC50 value of 4.2 nM.Finasteride can be used in the construction of animal models of hypospadias. |
| M5519 | Cilostazol | Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake. It can be used to construct animal models of deep vein thrombosis. |
| M5435 | Azathioprine | Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases. It can be used to construct animal models of colitis. |
| M5365 | Monobenzone | Monobenzone is a potent skin depigmenting agent that specifically inhibits tyrosinase and can be used in the construction of animal models of vitiligo and in studies related to skin pigmentation loss. |
| M4942 | Metoclopramide hydrochloride hydrate | Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is used as an antiemetic. It can be used to construct animal models of hyperprolactinemia. |
| M4914 | Tyloxapol | Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surfactant to aid liquefaction. |
| M4663 | Reserpine | Reserpine is an inhibitor of vesicular monoamine transporter protein 2 (VMAT2) that irreversibly blocks the H+-coupled vesicular monoamine transporters, VMAT1 and VMAT2. It can be used to construct animal models of depression. |
| M4282 | Monocrotaline | Monocrotaline (Crotaline) is an pyrrolizidine alkaloid extracted from the seeds of the Crotalaria spectabilis plant to induce pulmonary hypertension in rodents. |
| M3891 | Calcipotriol | Calcipotriol is a 1,25-Dihydroxyvitamin D3 analogue which is used for the research of psoriasis. *The compound is unstable in solutions, freshly prepared is recommended |
| M3738 | Oxonic acid potassium salt | Oxonic acid potassium salt is an inhibitor of uricase. |
| M3521 | Fluticasone propionate | Fluticasone propionate (Flonase, Veramyst) is a synthetic corticosteroid which is derived from fluticasone used to treat asthma and allergic rhinitis (hay fever). |
| M3463 | Prednisolone | Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. It can be used to construct autoimmune hepatitis models. |
| M3453 | Scopolamine hydrobromide | Scopolamine HBr is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.It can be used to construct animal models of dry eye. |
| M3384 | Diethylstilbestrol | Diethylstilbestrol is a synthetic nonsteroidal estrogen that can be used to construct animal models of primary dysmenorrhea. |
| M3325 | Captopril | Captopril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM. It can be used to construct animal models of heart failure. Captopril is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM. |
| M3232 | Cortisone acetate | Cortisone acetate is the acetate form of Cortisone, a steroid hormone and glucocorticoid that suppresses the immune system, thereby reducing inflammatory pain and swelling at the site of injury.Cortisone acetate and epinephrine, the primary hormones released by the body in response to stress, elevate blood pressure. They can be used to construct animal models of hypertension. |
| M3215 | Adenine | Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry. |
| M3186 | Isoprenaline hydrochloride | Isoproterenol hydrochloride is a non-selective β-adrenoceptor, inhibits the 3H-inositol phosphate accumulation with IC50 of 0.08 μM. |
| M2944 | Pilocarpine hydrochloride | Pilocarpine hydrochloride is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy. *The compound is unstable in solutions, freshly prepared is recommended |
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