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Pilocarpine hydrochloride

Cat. No. M2944
Pilocarpine hydrochloride Structure
Size Price Availability Quantity
100mg USD 45  USD50 In stock
500mg USD 85.5  USD95 In stock
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Quality Control
Biological Activity

Pilocarpine hydrochloride is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy.

*The compound is unstable in solutions, freshly prepared is recommended

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 244.72
Formula C11H16N2O2.HCl
CAS Number 54-71-7
Purity 99.76%
Solubility Water 30 mg/mL
DMSO 10 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




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