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Benzbromarone

Cat. No. M2440

All AbMole products are for research use only, cannot be used for human consumption.

Benzbromarone Structure
Size Price Availability Quantity
100mg USD 55  USD55 In stock
200mg USD 75  USD75 In stock
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Quality Control & Documentation
Biological Activity

Benzbromarone is a URAT1 inhibitor that inhibits MDCKII cells over-expressing URAT1 with an IC50 of 0.190 μM. Benzbromarone is also a CYP2C9 inhibitor, it binds to CYP2C9 with Ki value of 19.3 nM.

Chemical Information
Molecular Weight 424.08
Formula C17H12Br2O3
CAS Number 3562-84-3
Solubility (25°C) DMSO 80 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Esraa Abdel-Nassir Abdel-Razek, et al. Benzbromarone mitigates cisplatin nephrotoxicity involving enhanced peroxisome proliferator-activated receptor-alpha (PPAR-α) expression

[2] No authors listed. Benzbromarone

[3] Valderilio Feij Azevedo, et al. Benzbromarone in the treatment of gout

[4] Peng Sun, et al. Benzbromarone aggravates hepatic steatosis in obese individuals

[5] Ming-Han H Lee, et al. A benefit-risk assessment of benzbromarone in the treatment of gout. Was its withdrawal from the market in the best interest of patients?

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Keywords: Benzbromarone supplier, Animal Modeling, inhibitors, activators

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