| Cat.No. | Name | Information |
|---|---|---|
| M1969 | Doxorubicin HCL | Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. |
| M2082 | Streptozotocin | Streptozotocin (STZ) is a kind of glucosamine - nitrosourea derivative. *The compound is unstable in solutions, freshly prepared is recommended |
| M2227 | Imiquimod | Imiquimod (R837), an imidazoquinoline amine analog to guanosine, is a selective toll like receptor 7 (TLR7) agonist. with potent indirect antiviral activity. |
| M5152 | Sodium Butyrate | Sodium butyrate is the sodium salt of butyric acid, which has been reported to cause hyperacetylation of histones due to its role as a HDAC inhibitor with IC50 values of 0.3, 0.4, 0.3 mM for HDAC1, 2 and 7 respectively. Can be used to construct animal models of venous stenosis. |
| M3637 | Puromycin dihydrochloride | Puromycin dihydrochloride is an aminonucleoside antibiotic that acts as a protein synthesis inhibitor. |
| M3699 | Letrozole | Letrozole is an orally active, potent, selective, nonsteroidal, third-generation aromatase (CYP19A1) inhibitor, a synthetic benzyltriazole derivative, which is used in the construction of animal models of polycystic ovary syndrome (PCOS), as well as in studies related to postoperative hormone-responsive breast cancer. |
| M5688 | Heparin sodium | Heparin sodium salt, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. |
| M9524 | Lipopolysaccharides | Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. This product is derived from Escherichia coli O55:B5. |
| M6209 | Rotenone | Rotenone is an inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase, and is used to induce a Parkinson-like syndrome as an experimental model in rats. |
| M3671 | Cyclophosphamide monohydrate | Cyclophosphamide monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA. *The compound is unstable in solutions, freshly prepared is recommended |
| M2440 | Benzbromarone | Benzbromarone is a URAT1 inhibitor that inhibits MDCKII cells over-expressing URAT1 with an IC50 of 0.190 μM. |
| M2145 | Loperamide hydrochloride | Loperamide hydrochloride is a high affinity μ-opioid receptor agonist with peripheral selectivity with Ki values of 2, 48 and 1156 nM for μ-, δ- and κ-opioid receptors respectively. Loperamide hydrochloride is also a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. It can be used to construct animal models of functional constipation. |
| M54197 | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) is a minor component of CNS myelin. |
| M53993 | PLP (139-151) | PLP (139-151) is amino acid residue 139 to 151 of myelin proteolipid protein (PLP) used to induce experimental autoimmune encephalomyelitis (EAE). |
| M50254 | G6PI 325-339 (human) | G6PI 325-339 (human) is an efficient inducer of arthritis in B10.Q mice. |
| M50240 | Heparin sodium salt (MW 15kDa) | Heparin sodium salt (MW 15kDa) is a heparin polymer with a molecular weight of 15kDa.Heparin sodium salt is an anticoagulant that reversibly binds to antithrombin III (ATIII), thereby accelerating the rate of inactivation of Thrombin factor IIa and factor Xa by ATIII. Heparin sodium salt is used for blood collection and plasma preparation in experimental animals and for the construction of parenteral nutrition models in mice. |
| M49464 | 1-Butyl-1-nitrosourea | 1-Butyl-1-nitrosourea can be used to construct animal models of leukemia. |
| M40838 | Boromycin | Boromycin is a compound isolated from Streptomyces antibioticus and a boron-containing macrolide antibiotic with potent activity against a number of viruses, gram-positive bacteria and protozoan parasites. It can be used to induce a mouse model of pulmonary fibrosis and can be used in malaria-related studies. |
| M40796 | Dextrose iron | Dextrose iron can be used to construct animal models of iron overload. |
| M40783 | p-Chloroamphetamine hydrochloride | p-Chloroamphetamine hydrochloride, a neurotoxin that destroys serotonergic neurons, can be used to construct animal models of premature ejaculation. |
| M40478 | Scopolamine hydrochloride | Scopolamine hydrochloride is a non-selective and high affinity (≤1 nM) muscarinic antagonist that is used for the prevention of post-operative nausea and vomiting. Scopolamine readily passes the blood brain barrier. Scopolamine also reversibly inhibits 5-HT3 receptor-responses with an IC50 of 2.09 μM. |
| M25572 | Morrhuate sodium | Morrhuate sodium is the sodium salt of fatty acids in cod liver oil and can be used to construct rabbit osteomyelitis models. |
| M25570 | Coal Tar | Coal Tar is a product obtained from the dry distillation process of coal and can be used to construct a rabbit ear acne model. |
| M6863 | Kainic acid | Kainic acid is a potent excitotoxic agent and neurotoxin, as well as an agonist of the ionotropic glutamate receptor subtype. In addition, Kainic acid can be used to construct animal models of epilepsy. |
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