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Scopolamine hydrochloride

Cat. No. M40478

All AbMole products are for research use only, cannot be used for human consumption.

Scopolamine hydrochloride Structure

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Quality Control & Documentation
Biological Activity

Scopolamine hydrochloride is a non-selective and high affinity (≤1 nM) muscarinic antagonist that is used for the prevention of post-operative nausea and vomiting. Scopolamine readily passes the blood brain barrier. Scopolamine also reversibly inhibits 5-HT3 receptor-responses with an IC50 of 2.09 μM.

Chemical Information
Molecular Weight 339.81
Formula C17H22ClNO4
CAS Number 55-16-3
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Camarin E Rolle et al. JAMA Psychiatry. Cortical Connectivity Moderators of Antidepressant vs Placebo Treatment Response in Major Depressive Disorder: Secondary Analysis of a Randomized Clinical Trial

[2] Christopher Nile et al. mSphere. Repurposing Pilocarpine Hydrochloride for Treatment of Candida albicans Infections

[3] Dengqin Wang et al. Exp Ther Med. Protective effects of scopolamine and penehyclidine hydrochloride on acute cerebral ischemia-reperfusion injury after cardiopulmonary resuscitation and effects on cytokines

[4] T C Hain et al. Arch Otolaryngol Head Neck Surg. Mal de debarquement

[5] D J Greenblatt et al. JAMA. Intramuscular injection-site complications

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