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Animal Modeling

Cat.No.  Name Information
M1969 Doxorubicin HCL Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
M2082 Streptozotocin Streptozotocin (STZ) is a kind of glucosamine - nitrosourea derivative. *The compound is unstable in solutions, freshly prepared is recommended
M2227 Imiquimod Imiquimod (R837), an imidazoquinoline amine analog to guanosine, is a selective toll like receptor 7 (TLR7) agonist. with potent indirect antiviral activity.
M5152 Sodium Butyrate Sodium butyrate is the sodium salt of butyric acid, which has been reported to cause hyperacetylation of histones due to its role as a HDAC inhibitor with IC50 values of 0.3, 0.4, 0.3 mM for HDAC1, 2 and 7 respectively. Can be used to construct animal models of venous stenosis.
M5791 Mitomycin C Mitomycin C (Ametycine) is an antineoplastic antibiotic by inhibiting DNA synthesis.
M3637 Puromycin dihydrochloride Puromycin dihydrochloride is an aminonucleoside antibiotic that acts as a protein synthesis inhibitor.
M6033 Dihydrotestosterone Dihydrotestosterone is an androgen (male hormone). Specifically it's the strongest of the androgens. It can be used to construct animal models of polycystic ovary syndrome (PCOS).
M3699 Letrozole Letrozole is an orally active, potent, selective, nonsteroidal, third-generation aromatase (CYP19A1) inhibitor, a synthetic benzyltriazole derivative, which is used in the construction of animal models of polycystic ovary syndrome (PCOS), as well as in studies related to postoperative hormone-responsive breast cancer.
M5688 Heparin sodium Heparin sodium salt, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule.
M9524 Lipopolysaccharides Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. This product is derived from Escherichia coli O55:B5.
M9941 Hyaluronidase (from sheep testes) Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds. In addition, Hyaluronidase can be used to construct animal models of retinal detachment.
M9907 Freund′s Adjuvant, Incomplete Freund′s adjuvant (incomplete) lacks the Mycobacteria found in Complete Freund′s Adjuvant so it minimizes the side-effects. It is used for boost injections. It was used to emulsify antigens that are injected into animals to produce monoclonal antibodies from the antiserum.
M9887 Concanavalin A Concanavalin A is a protein containing only β-sheets in its structure, and belongs to the legume lectins family.It can be used to construct dry eye models, as well as autoimmune hepatitis models.
M9831 Aluminium hydroxide Aluminum Hydroxide is an orally active main form of aluminum used as adjuvant.
M9806 L-Cysteine L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine.
M9800 Oxalic Acid Oxalic Acid is a strong dicarboxylic acid occurring in many plants and vegetables and directly inhibits the OGA-stimulated production of H2O2 by soybean cells, even in the absence of other fungal components.Oxalic Acid can be used in the construction of animal models of renal disease.
M9797 1-Methyl-3-nitro-1-nitrosoguanidine (MNNG) Methylnitronitrosoguanidine (MNNG) is an alkylating agent with toxic and mutagenic effects.
M9760 Chicken egg albumin Chicken egg albumin, or ovalbumin, is the major protein constituent of egg whites. Chicken egg albumin is a phosphorylated glycoprotein.
M9616 Bovine Serum Albumin Bovine Serum Albumin (BSA) is a globular protein that is used in numerous biochemical applications.
M9337 Sodium iodoacetate Sodium iodoacetate induces chondrocyte metabolic disorders for the construction of a rat arthritis (OA) model. (This product is light sensitive)
M9181 8-OH-DPAT 8-OH-DPAT (8-Hydroxy-DPAT) is a potent and selective 5-HT agonist, with a pIC50 of 8.19 for 5-HT1A.
M9061 Dehydroepiandrosterone Dehydroepiandrosterone is a potent anti-apoptotic factor with some degree of androgenic activity and is a low affinity (Ki = 1 micron) partial agonist for the androgen receptor (AR). In addition, Dehydroepiandrosterone can also be used to construct a rat polycystic ovary syndrome model.
M8019 Pilocarpine nitrate salt Pilocarpine nitrate salt is a non-selective muscarinic acetylcholine receptor (AChR) agonist used to construct experimental models of epilepsy. In addition, Pilocarpine constricts the pupil, enhances depth of field, and improves near and intermediate vision, which can be used in studies related to presbyopia.
M7869 Kainic acid monohydrate Kainic acid monohydrate is an agonist at the kainate class of ionotropic glutamate receptors, which induces seizures and neurodegeneration in vivo and is used to induce experimental epilepsy in rodents and study the mechanisms of excitation-induced neuronal apoptosis.
M6894 L-Arginine L-Arginine is a endogenous substrate for NOS.
M6339 3-Nitropropionic acid 3-Nitropropionic acid is a irreversible mitochondrial respiratory complex II inhibitor.
M6240 Angiotensin II human Angiotensin II human is converted by Angiotensin I through removal of two C-terminal residues by the enzyme angiotensin-converting enzyme (ACE). Angiotensin II is mediated by AT1 and AT2 receptors, which are seven transmembrane glycoproteins with 30% sequence similarity. Keep away from light and prepare for use now.
M6047 Ursodiol Ursodiol reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones with an IC50 of 0.22 μM. Ursodeoxycholic acid (UDCA), which reduces FXR and closes the ACE2 channel. It can be used to construct animal models of cholelithiasis.
M5902 Progesterone Progesterone is an endogenous steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. A potent agonist of the nuclear progesterone receptor (nPR) with Kd of 1 nM; An agonist of the membrane progesterone receptors(mPRs); An antagonist of the σ1 receptor. It can be used to construct a model of melasma as well as a model of fibrocystic hyperplasia of the breast.
M5845 Oxytocin Oxytocin (α-Hypophamine) is a mammalian neurohypophysial hormone; its actions are mediated by specific, high-affinity oxytocin receptors; ligand of oxytocin receptor.It can be used to construct animal models of primary dysmenorrhea.




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