| Cat.No. | Name | Information |
|---|---|---|
| M1969 | Doxorubicin HCL | Doxorubicin HCl (Adriamycin, DOX, RP 13057) hydrochloride is an antibiotic-like agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. |
| M2082 | Streptozotocin | Streptozotocin (STZ) is a kind of glucosamine - nitrosourea derivative. *The compound is unstable in solutions, freshly prepared is recommended |
| M2227 | Imiquimod | Imiquimod (R837), an imidazoquinoline amine analog to guanosine, is a selective toll like receptor 7 (TLR7) agonist. with potent indirect antiviral activity. |
| M5152 | Sodium Butyrate | Sodium butyrate is the sodium salt of butyric acid, which has been reported to cause hyperacetylation of histones due to its role as a HDAC inhibitor with IC50 values of 0.3, 0.4, 0.3 mM for HDAC1, 2 and 7 respectively. Can be used to construct animal models of venous stenosis. |
| M3637 | Puromycin dihydrochloride | Puromycin dihydrochloride is an aminonucleoside antibiotic that acts as a protein synthesis inhibitor. |
| M3699 | Letrozole | Letrozole is an orally active, potent, selective, nonsteroidal, third-generation aromatase (CYP19A1) inhibitor, a synthetic benzyltriazole derivative, which is used in the construction of animal models of polycystic ovary syndrome (PCOS), as well as in studies related to postoperative hormone-responsive breast cancer. |
| M5688 | Heparin sodium | Heparin sodium salt, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. |
| M9524 | Lipopolysaccharides | Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. This product is derived from Escherichia coli O55:B5. |
| M6209 | Rotenone | Rotenone is an inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase, and is used to induce a Parkinson-like syndrome as an experimental model in rats. |
| M3671 | Cyclophosphamide monohydrate | Cyclophosphamide monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA. *The compound is unstable in solutions, freshly prepared is recommended |
| M9907 | Freund′s Adjuvant, Incomplete | Freund′s adjuvant (incomplete) lacks the Mycobacteria found in Complete Freund′s Adjuvant so it minimizes the side-effects. It is used for boost injections. It was used to emulsify antigens that are injected into animals to produce monoclonal antibodies from the antiserum. |
| M9831 | Aluminium hydroxide | Aluminum Hydroxide is an orally active main form of aluminum used as adjuvant. |
| M9806 | L-Cysteine | L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. |
| M9800 | Oxalic Acid | Oxalic Acid is a strong dicarboxylic acid occurring in many plants and vegetables and directly inhibits the OGA-stimulated production of H2O2 by soybean cells, even in the absence of other fungal components.Oxalic Acid can be used in the construction of animal models of renal disease. |
| M9760 | Chicken egg albumin | Chicken egg albumin, or ovalbumin, is the major protein constituent of egg whites. Chicken egg albumin is a phosphorylated glycoprotein. |
| M9337 | Sodium iodoacetate | Sodium iodoacetate induces chondrocyte metabolic disorders for the construction of a rat arthritis (OA) model. (This product is light sensitive) |
| M9181 | 8-OH-DPAT | 8-OH-DPAT (8-Hydroxy-DPAT) is a potent and selective 5-HT agonist, with a pIC50 of 8.19 for 5-HT1A. |
| M9061 | Dehydroepiandrosterone | Dehydroepiandrosterone is a potent anti-apoptotic factor with some degree of androgenic activity and is a low affinity (Ki = 1 micron) partial agonist for the androgen receptor (AR). In addition, Dehydroepiandrosterone can also be used to construct a rat polycystic ovary syndrome model. |
| M8019 | Pilocarpine nitrate salt | Pilocarpine nitrate salt is a non-selective muscarinic acetylcholine receptor (AChR) agonist used to construct experimental models of epilepsy. In addition, Pilocarpine constricts the pupil, enhances depth of field, and improves near and intermediate vision, which can be used in studies related to presbyopia. |
| M6339 | 3-Nitropropionic acid | 3-Nitropropionic acid is a irreversible mitochondrial respiratory complex II inhibitor. |
| M6047 | Ursodiol | Ursodiol reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones with an IC50 of 0.22 μM. Ursodeoxycholic acid (UDCA), which reduces FXR and closes the ACE2 channel. It can be used to construct animal models of cholelithiasis. |
| M5902 | Progesterone | Progesterone is an endogenous steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. A potent agonist of the nuclear progesterone receptor (nPR) with Kd of 1 nM; An agonist of the membrane progesterone receptors(mPRs); An antagonist of the σ1 receptor. It can be used to construct a model of melasma as well as a model of fibrocystic hyperplasia of the breast. |
| M5845 | Oxytocin | Oxytocin (α-Hypophamine) is a mammalian neurohypophysial hormone; its actions are mediated by specific, high-affinity oxytocin receptors; ligand of oxytocin receptor.It can be used to construct animal models of primary dysmenorrhea. |
| M5666 | Furazolidone | Furazolidone is a synthetic nitrofuran derivative with bactericidal or bacteriostatic activity when used against Gram-positive and Gram-negative bacteria. It can be used to construct animal models of cardiomyopathy. |
| M5647 | Finasteride | Finasteride is an orally active, potent and reversible steroid type II 5α-reductase (SRD5A2) inhibitor with an IC50 value of 4.2 nM.Finasteride can be used in the construction of animal models of hypospadias. |
| M5519 | Cilostazol | Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake. It can be used to construct animal models of deep vein thrombosis. |
| M5435 | Azathioprine | Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases. It can be used to construct animal models of colitis. |
| M5426 | Aspirin | Aspirin is a salicylate, and irreversible COX1 and COX2 inhibitor, used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. |
| M5365 | Monobenzone | Monobenzone is a potent skin depigmenting agent that specifically inhibits tyrosinase and can be used in the construction of animal models of vitiligo and in studies related to skin pigmentation loss. |
| M4942 | Metoclopramide hydrochloride hydrate | Metoclopramide hydrochloride hydrate is a dopamine D2 antagonist that is used as an antiemetic. It can be used to construct animal models of hyperprolactinemia. |
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