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Dexamethasone Sodium Phosphate

Cat. No. M2626

All AbMole products are for research use only, cannot be used for human consumption.

Dexamethasone Sodium Phosphate Structure
Synonym:

Dexamethasone phosphate disodium

Size Price Availability Quantity
50mg USD 30  USD30 In stock
100mg USD 45  USD45 In stock
500mg USD 65  USD65 In stock
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Quality Control & Documentation
Biological Activity

Dexamethasone Sodium Phosphate is a glucocorticoid receptor agonist that induces the production of lipocortin, a phospholipase A2 inhibitory protein. Dexamethasone inhibits autophagy levels in damaged cells in a dose-dependent manner. It can be used to construct models of allergic conjunctivitis. Dexamethasone Sodium Phosphate is an interleukin receptor inhibitor and also suppresses COX-2.

Chemical Information
Molecular Weight 516.4
Formula C22H30FO8P.2Na
CAS Number 55203-24-2
Solubility (25°C) Water 100 mg/mL (ultrasonic)
Storage 2-8°C, dry, sealed
References

[1] Kamran Hosseini, et al. Pharmacokinetic study of dexamethasone disodium phosphate using intravitreal, subconjunctival, and intravenous delivery routes in rabbits

[2] Kim JB, et al. Brain Res. Dexamethasone inhibits proliferation of adult hippocampal neurogenesis in vivo and in vitro.

[3] Yamamoto K, et al. FEBS Lett. Suppression of cyclooxygenase-2 gene transcription by humulon of beer hop extract studied with reference to glucocorticoid.

[4] Blanco FJ, et al. J Rheumatol. Effect of antiinflammatory drugs on COX-1 and COX-2 activity in human articular chondrocytes.

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Keywords: Dexamethasone Sodium Phosphate, Dexamethasone phosphate disodium supplier, Animal Modeling, inhibitors, activators

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