Elastase from porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide.
Powder -20°C 3 years ; 4°C 2 years
In solvent -80°C 6 months ; -20°C 1 month
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
 T Teshima, et al. J Biol Chem. A new class of heterocyclic serine protease inhibitors. Inhibition of human leukocyte elastase, porcine pancreatic elastase, cathepsin G, and bovine chymotrypsin A alpha with substituted benzoxazinones, quinazolines, and anthranilates
|Related Animal Modeling Products|
N-Butyl-N-(4-hydroxybutyl)nitrosamine can be used to construct animal models of bladder cancer (BLCA).
Boromycin is a compound isolated from Streptomyces antibioticus and a boron-containing macrolide antibiotic with potent activity against a number of viruses, gram-positive bacteria and protozoan parasites. It can be used to induce a mouse model of pulmonary fibrosis and can be used in malaria-related studies.
Dextrose iron can be used to construct animal models of iron overload.
Prednisone acetate is the acetate form of Prednisone and a glucocorticoid receptor agonist with anti-inflammatory and immunomodulatory properties. It can be used to construct animal models of Kawasaki disease.
Carrageenan is a biochemical reagent that can be used to construct animal models of chronic non-bacterial prostatitis, models of synovitis, and models of prostatitis.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.