TRP Channel Transient Receptor Potential Channel

Cat.No.	Name	Information
M6494	BCTC	BCTC is a tRPV1 antagonist. BCTC is also a potent and specific inhibitor of transient receptor potential cation channel subfamily M member 8 (TRPM8) in prostate cancer (PCa) DU145 cells.
M3422	Capsaicin	Capsaicin is an active component of chili peppers, which are plants belonging to the genus Capsicum.
M7698	Capsazepine	Capsazepine is a specific vanilloid receptor antagonist; synthetic analog of capsaicin.
M10315	MK6-83	MK6-83 is an agonist of the transient receptor potential channel ML3 (TRPML3).
M9962	Nonivamide	Nonivamide (also called pelargonic acid vanillylamide or PAVA) can activate the TRPV1 receptor, thus, stimulate the firing rate of dopaminergic neurons in the ventral tegmental area of the brain and to increase the expression of the serotonin receptor gene HTR2A.
M2960	Probenecid	Probenecid is a classical competitive inhibitor of organic anion transport, which is also a TRPV2 agonist and an inhibitor of TAS2R16.
M7816	GSK1016790A	GSK1016790A is a novel and potent TRPV4 channel agonist.
M52703	N-Oleoyl valine	N-Oleoyl valine is a N-acyl valine compound that acts as a TRPV3 receptor antagonist.
M52702	TAT-M2NX	TAT-M2NX (tatM2NX) is a TRPM2 inhibitor with specific neuroprotective activity in male mice.
M52701	SOR-C13	SOR-C13, a carboxy-terminal truncated peptide, is a high-affinity TRPV6 antagonist with an IC50 value of 14 nM.
M44794	beta-Eudesmol	Beta-Eudesmol is a natural oxygenated sesquiterpene, activates hTRPA1, with an EC50 of 32.5 μM. Beta-Eudesmol increases appetite through TRPA1.
M43953	GFB-887	GFB-887 is an inhibitor of transient receptor potential channels 4 and 5 (TRPC4/5) and can be used in studies related to anxiety disorders.
M43944	Tivanisiran	Tivanisiran is an siRNA that silences TRPV1 mRNA and can be used in studies related to dry eye.
M42267	MK-2295	MK-2295 (NGD-8243) is a TRPV1 antagonist.
M42266	KM-001	KM-001 is a potent and selective TRPV3 antagonist.
M42265	Diisopropyl adipate	Diisopropyl adipate is an alternative plasticizer and a TRPA1 activator.
M42264	BTD	BTD is a selective transient receptor potential canonical 5 (TRPC5) activator.
M42263	TRPV4 antagonist 4	TRPV4 antagonist 4 is a potent TRPV4 antagonist with an IC50 value of 22.65 nM.
M42262	TRPA1-IN-2	TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.
M42261	Xeniafaraunol A	Xeniafaraunol A is a potent transient receptor potential melastatin 7 (TRPM7) inhibitor.
M42260	TRPC3/6-IN-2	TRPC3/6-IN-2 is a potent TRPC3/6 inhibitor with IC50 values of 16 nM and 29.8 nM for TRPC3 and TRPC6, respectively.
M42259	Farnesyl Pyrophosphate ammonium	Farnesyl Pyrophosphate ammonium salt, a 15-carbon isoprenoid, is a metabolic intermediate of the mevalonate (MVA) pathway.
M40932	GDC-6599	GDC-6599 is a first-in-class, orally effective TRPA1 inhibitor for studies related to chronic cough and asthma.
M40892	Acetaldehyde	Acetaldehyde is a TRP anchor protein 1 (TRPA1) agonist that is converted to non-toxic acetic acid by acetaldehyde dehydrogenase (ALDH).
M31420	Adenosine 5′-diphosphoribose sodium	Adenosine 5′-diphosphoribose sodium is a metabolite of nicotinamide adenine nucleotides (NAD+), as well as a potent intracellular Ca2+-permeable cation TRPM2 channel activator, and enhances autophagy.
M31419	JNJ-28583113	JNJ-28583113 is a brain-permeable TRPM2 antagonist and blocks phosphorylation of GSK3α and β subunits by inhibiting TRPM2. In addition, JNJ-28583113 inhibits cytokine release from microglia in response to pro-inflammatory stimuli. It has the function of protecting cells from oxidative stress-induced cell death.
M31054	L-R4W2 TFA	L-R4W2 TFA is a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), with an IC50 of 0.1 μM. L-R4W2 TFA may act as a potent analgesic.

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TRP Channel Transient Receptor Potential Channel

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