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Capsazepine

Cat. No. M7698

All AbMole products are for research use only, cannot be used for human consumption.

Capsazepine Structure
Size Price Availability Quantity
1mg USD 25  USD25 In stock
5mg USD 49  USD49 In stock
10mg USD 79  USD79 In stock
25mg USD 149  USD149 In stock
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Quality Control & Documentation
Biological Activity

Capsazepine is a specific vanilloid receptor antagonist; synthetic analog of capsaicin.

Product Citations
Chemical Information
Molecular Weight 376.9
Formula C19H21ClN2O2S
CAS Number 138977-28-3
Solubility (25°C) DMSO 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Darine Fakih, et al. Capsazepine decreases corneal pain syndrome in severe dry eye disease

[2] Min Hee Yang, et al. Pleiotropic Pharmacological Actions of Capsazepine, a Synthetic Analogue of Capsaicin, against Various Cancers and Inflammatory Diseases

[3] Danilo De Gregorio, et al. Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain

[4] Guang-Feng Zuo, et al. Capsazepine concentration dependently inhibits currents in HEK 293 cells mediated by human hyperpolarization-activated cyclic nucleotide-gated 2 and 4 channels

[5] Hsiu-Peng Teng, et al. Capsazepine elevates intracellular Ca2+ in human osteosarcoma cells, questioning its selectivity as a vanilloid receptor antagonist

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Keywords: Capsazepine supplier, TRP Channel, inhibitors, activators

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